Evidence map›Paper›PMID 32827786›Full record

ArticleJournal of biomechanics2020

Dysplastic hip anatomy alters muscle moment arm lengths, lines of action, and contributions to joint reaction forces during gait.

Ke Song, Brecca M M Gaffney, Kevin B Shelburne, Cecilia Pascual-Garrido, John C Clohisy, Michael D Harris

Open access · greenAbstract read
In one paragraph

Article in Journal of biomechanics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Hamstring Mechanics During Acceleration, Deceleration and Sidestep Cutting.Scandinavian journal of medicine & science in sports · 2026
    Article
  3. Article
  4. Article
  5. Load Management After Gluteal Tendon Repair: A Controlled Laboratory Study.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Using Dynamic Joint Space During Physiological Loading to Objectively Measure Hip Stability.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ke SongProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO, USA.
Brecca M M GaffneyProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Kevin B ShelburneDepartment of Mechanical and Materials Engineering, University of Denver, Denver, CO, USA.
Cecilia Pascual-GarridoDepartment of Orthopaedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
John C ClohisyDepartment of Orthopaedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Michael D HarrisProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO, USA; Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO, USA; Department of Orthopaedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, USA. Electronic address: harrismi@wustl.edu.
Washington University in St. Louis · USUniversity of Denver · US

Funding

Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI Simon Yue-Cheong Tang · 2019 to 2026
$6.8M
Mediators of the OA Cascade in the Pre-Arthritic HipK08AR077740 · NIAMS · WASHINGTON UNIVERSITY · PI PASCUAL-GARRIDO, CECILIA · 2020 to 2024
$779k
Muscle Geometry and its Influence on Function in Patients with Developmental Dysplasia of the HipK01AR072072 · NIAMS · WASHINGTON UNIVERSITY · PI HARRIS, MICHAEL D · 2018 to 2022
$554k
NIAMS NIH HHS K01 AR072072NIAMS NIH HHS K08 AR077740NIAMS NIH HHS P30 AR074992
6 · The paper itself

Abstract

Developmental dysplasia of the hip (DDH) is characterized by abnormal bony anatomy, which causes detrimental hip joint loading and leads to secondary osteoarthritis. Hip joint loading depends, in part, on muscle-induced joint reaction forces (JRFs), and therefore, is influenced by hip muscle moment arm lengths (MALs) and lines of action (LoAs). The current study used subject-specific musculoskeletal models and in-vivo motion analysis to quantify the effects of DDH bony anatomy on dynamic muscle MALs, LoAs, and their contributions to JRF peaks during early (~17%) and late-stance (~52%) of gait. Compared to healthy hips (N = 15, 16-39 y/o), the abductor muscles in patients with untreated DDH (N = 15, 16-39 y/o) had smaller abduction MALs (e.g. anterior gluteus medius, 35.3 vs. 41.6 mm in early stance, 45.4 vs. 52.6 mm late stance, p ≤ 0.01) and more medially-directed LoAs. Abduction-adduction and rotation MALs also differed for major hip flexors such as rectus femoris and iliacus. The altered MALs in DDH corresponded to higher hip abductor forces, medial JRFs (1.26 vs. 0.87 × BW early stance, p = 0.03), and resultant JRFs (5.71 vs. 4.97 × BW late stance, p = 0.05). DDH anatomy not only affected hip muscle force generation in the primary plane of function, but also their out-of-plane mechanics, which collectively elevated JRFs. Overall, hip muscle MALs and their contributions to JRFs were significantly altered by DDH bony anatomy. Therefore, to better understand the mechanisms of joint degeneration and improve the efficacy of treatments for DDH, the dynamic anatomy-force relationships and multi-planar functions of the whole hip musculature must be collectively considered.

Indexed as

ArmGaitBiomechanical PhenomenaHipHip JointHumansMuscle, SkeletalDevelopmental dysplasia of the hipJoint reaction forceLine of actionMuscle moment armMusculoskeletal modeling

Identifiers

PMID32827786
PMCPMC7737424
OpenAlexW3044037288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.