ArticleJournal of sport and health science2021
Mortality in relation to changes in physical activity in middle-aged to older Chinese: An 8-year follow-up of the Guangzhou Biobank Cohort Study.
Article in Journal of sport and health science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Physical activity trajectories and accumulation over adulthood and their associations with all-cause and cause-specific mortality: a systematic review and meta-analysis.British journal of sports medicine · 2025Pooled it
- Effects of multidomain lifestyle intervention on frailty among older men and women - a secondary analysis of a randomized clinical trial.Annals of medicine · 2025Trial
- Association between physical activity score and incident hypertension among Chinese adults aged 65 years and older: a national prospective cohort study.Journal of human hypertension · 2026Article
- Associations of sleep duration, physical activity, and longitudinal changes with the risk of fatal stroke occurrence in middle-aged to older individuals : Physical activity, sleep duration, and risk of fatal stroke.BMC public health · 2026Article
- Trajectories of lipid profile with cognitive function: 12-year follow-up of Guangzhou Biobank cohort study.European archives of psychiatry and clinical neuroscience · 2026Article
- Construction and validation of a novel nutrient-based index for risk of aging using an interpretable machine learning framework: results from two population-based studies.Nutrition journal · 2025Article
- Exercise attenuates the hallmarks of aging: Novel perspectives.Journal of sport and health science · 2025Review
- Changing patterns and associated factors of exercise participation and physical activity levels among middle-aged and older adults from 2011-2020 in China.The international journal of behavioral nutrition and physical activity · 2025Article
- Optimal sleep timing revealed: a new perspective on reducing all-cause mortality and cardiovascular disease-cause mortality in older adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Increasing the health span: unique role for exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Review
- Association of changes in overall and specific leisure activities with long-term all-cause mortality in older adults: a nationwide cohort study.Journal of global health · 2025Article
- Physical activity, Vitamin D, and all-cause/cardiovascular mortality: a prospective study in older Chinese adults.BMC geriatrics · 2025Article
- Longitudinal Association of Changes in Metabolic Syndrome with Cognitive Function: 12-Year Follow-up of the Guangzhou Biobank Cohort Study.Diabetes & metabolism journal · 2025Article
- Exercise Mediates Noncoding RNAs in Cardiovascular Diseases: Pathophysiological Roles and Clinical Application.Expert reviews in molecular medicine · 2024Review
- Associations Between Changes in Physical Activity and Risk of All-Cause Mortality in Adults With/Without Hypertension - China, 2010-2022.China CDC weekly · 2024Article
- Article
- Influencing Factors on Cardiovascular Health in China.Journal of geriatric cardiology : JGC · 2024Article
- Association of fish and meat consumption with non-alcoholic fatty liver disease: Guangzhou Biobank Cohort Study.BMC public health · 2023Article
- Obesity indicators as mediators of the association between age at menopause and blood pressure values.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Cereal intake and mortality in older Chinese: a 15-year follow-up of a prospective cohort study.European journal of nutrition · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhysical activity (PA) is generally encouraged. Studies from developed countries in the West have shown that maintenance of adequate PA or increasing PA are associated with lower mortality risk. It is unclear whether these associations apply to an older Chinese population. Hence, we examined the changes in PA prospectively among a middle-aged and older Chinese population over an average of 4 years and explored their subsequent mortality risks.
methodsMetabolic equivalent scores of PA among participants in the Guangzhou Biobank Cohort Study were calculated. Participants were divided into 3 groups related to PA level, and changes in PA were classified into 9 categories. Information on vital status and causes of death from March 2008 to December 2012 (the first repeated examination) until December 31, 2017, was obtained via record linkage with the Death Registry.
resultsOf 18,104 participants aged 61.21 ± 6.85 years (mean ± SD), 1461 deaths occurred within 141,417 person-years. Compared to participants who maintained moderate PA, those who decreased PA from moderate or high levels to a low level had increased risks for all-cause mortality (hazard ratio (HR) = 1.47, 95% confidence interval (95%CI): 1.11-1.96). Participants who maintained a high level of PA (HR = 0.83, 95%CI: 0.70-0.98) or increased PA from low to high levels (HR = 0.71, 95%CI: 0.52-0.97) showed lower all-cause mortality risks. Those who maintained low PA levels showed a higher all-cause mortality risk, whereas those who increased their PA levels showed a non-significantly lower risk. Similar results were found for cardiovascular disease risk.
conclusionEven at an older age, maintaining a high PA level or increasing PA from low to high levels results in lower mortality risks, suggesting that substantial health benefits might be achieved by maintaining or increasing engagement in adequate levels of PA. The increased risk of maintaining a low PA level or decreasing PA to a low level warrants the attention of public health officials and clinicians.
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