Evidence map›Paper›PMID 32827468›Full record

ArticleThe American journal of medicine2021

Heart Failure Risk Distribution and Trends in the United States Population, NHANES 1999-2016.

Peter A Glynn, Hongyan Ning, Aakash Bavishi, Priya M Freaney, Sanjiv Shah, Clyde W Yancy, Donald M Lloyd-Jones, Sadiya S Khan

Open access · greenAbstract read
In one paragraph

Article in The American journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Peter A GlynnDepartment of Medicine.
Hongyan NingDepartment of Preventive Medicine.
Aakash BavishiDepartment of Medicine.
Priya M FreaneyDepartment of Preventive Medicine; Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Sanjiv ShahDivision of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Clyde W YancyDivision of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Donald M Lloyd-JonesDepartment of Preventive Medicine; Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Sadiya S KhanDepartment of Preventive Medicine; Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address: s-khan-1@northwestern.edu.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Northwestern University Clinical and Translational Science Institute (NUCATS)KL2TR001424 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2015 to 2023
$8.1M
NCATS NIH HHS KL2 TR001424NCATS NIH HHS UL1 TR001422
6 · The paper itself

Abstract

backgroundImplementation of effective preventive interventions requires identification of high-risk individuals. We sought to define the distribution and trends of heart failure risk in the US population.

methodsWe calculated 10-year predicted heart failure risk among a representative sample of US adults aged 30-79 years, without baseline cardiovascular disease, from the National Health and Nutrition Examination Surveys (NHANES) 1999-2016. We used the published Pooled Cohort Equations to Prevent Heart Failure (PCP-HF) model, which integrates demographic and risk factor data, to estimate 10-year heart failure risk. Participants were stratified by NHANES cycle, sex, age, and race/ethnicity and by 10-year heart failure risk, defined as low (<1%), intermediate (1% to <5%), and high (≥5%).

resultsFrom 1999-2000 to 2015-2016, mean predicted 10-year heart failure risk increased significantly from 2.0% to 3.0% (P < .05) in the population, most notably among non-Hispanic black (2.1% to 3.7%) and non-Hispanic white (2.4% to 3.6%) men. In 2013-2016, 17.6% of the studied population was at high predicted 10-year heart failure risk. The prevalence of high predicted heart failure risk was highest among non-Hispanic black men (23.1%), followed by non-Hispanic white men (19.2%) and non-Hispanic white women (17.9%). DISCUSSION: Mean population risk of heart failure increased significantly from 1999-2016. A substantial proportion of US adults are at high 10-year heart failure risk (≥5%), particularly non-Hispanic black men. These data underscore the importance of identifiying individuals at increased heart failure risk for targeted prevention measures to reduce the future burden of heart failure.

Indexed as

AdultAgedBlack or African AmericanCross-Sectional StudiesFemaleHeart FailureHumansMaleMiddle AgedNutrition SurveysRisk AssessmentTime FactorsUnited StatesWhite PeopleHealth disparitiesHeart failurePreventionRisk stratification

Identifiers

PMID32827468
PMCPMC7895865
OpenAlexW3080659379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.