Evidence map›Paper›PMID 32827459›Full record

ArticleAmerican heart journal2020

Menopausal age and left ventricular remodeling by cardiac magnetic resonance imaging among 14,550 women.

Michael C Honigberg, James P Pirruccello, Krishna Aragam, Amy A Sarma, Nandita S Scott, Malissa J Wood, Pradeep Natarajan

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in American heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Impact of ovary-intact menopause in a mouse model of heart failure with preserved ejection fraction.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Michael C HonigbergCardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA; Corrigan Women's Heart Health Program, Massachusetts General Hospital, Boston, MA.
James P PirruccelloCardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
Krishna AragamCardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
Amy A SarmaCardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Corrigan Women's Heart Health Program, Massachusetts General Hospital, Boston, MA.
Nandita S ScottCardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Corrigan Women's Heart Health Program, Massachusetts General Hospital, Boston, MA.
Malissa J WoodCardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Corrigan Women's Heart Health Program, Massachusetts General Hospital, Boston, MA.
Pradeep NatarajanCardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA. Electronic address: pnatarajan@mgh.harvard.edu.
Massachusetts General Hospital · USBroad Institute · USHarvard University · US

Funding

Noninvasive Cardiovascular Imaging Research Training ProgramT32HL094301 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Marcelo F DI CARLI · 2010 to 2026
$7.8M
NHLBI NIH HHS T32 HL094301
6 · The paper itself

Abstract

The present study included 14,550 postmenopausal female participants in the UK Biobank who completed cardiac magnetic resonance imaging. Earlier age at menopause was significantly and independently associated with smaller left ventricular end-diastolic volume and smaller stroke volume, a pattern suggesting acceleration of previously described age-related left ventricular remodeling. These findings may have implications for understanding mechanisms of heart failure, specifically heart failure with preserved ejection fraction, among women with early menopause.

Indexed as

Heart VentriclesFemaleHeart FailureHumansMagnetic Resonance Imaging, CineMenopauseMenopause, PrematureMiddle AgedOrgan SizeStroke VolumeVentricular Remodeling

Identifiers

PMID32827459
PMCPMC7669696
OpenAlexW3073680107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.