Evidence map›Paper›PMID 32826896›Full record

ArticleNature communications2020

Taf14 recognizes a common motif in transcriptional machineries and facilitates their clustering by phase separation.

Guochao Chen, Duo Wang, Bin Wu, Fuxiang Yan, Hongjuan Xue, Quanmeng Wang, Shu Quan, Yong Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Transcription regulation by biomolecular condensates.Nature reviews. Molecular cell biology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Frontiers in epigenetics and epigenomics · 2024
    Article
  14. Differences and similarities in recognition of co-factors by Taf14.Biochimica et biophysica acta. Gene regulatory mechanisms · 2023
    Article
  15. Article
  16. Article
  17. Phase separation in fungi.Nature microbiology · 2023
    Review
  18. Article
  19. Taf2 mediates DNA binding of Taf14.Nature communications · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Guochao Chen *State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, 200031, China.
Duo Wang *State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, 200031, China.
Bin Wu *National Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210, China.
Fuxiang YanState Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, 200031, China.
Hongjuan XueNational Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210, China.
Quanmeng WangNational Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, 430070, China.
Shu QuanState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China.ORCID http://orcid.org/0000-0002-6672-4947
Yong ChenState Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, 200031, China. yongchen@sibcb.ac.cn.ORCID http://orcid.org/0000-0001-5857-6086
Chinese Academy of Sciences · CNEast China University of Science and Technology · CNHuazhong Agricultural University · CNShanghaiTech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saccharomyces cerevisiae TBP associated factor 14 (Taf14) is a well-studied transcriptional regulator that controls diverse physiological processes and that physically interacts with at least seven nuclear complexes in yeast. Despite multiple previous Taf14 structural studies, the nature of its disparate transcriptional regulatory functions remains opaque. Here, we demonstrate that the extra-terminal (ET) domain of Taf14 (Taf14

Indexed as

Carrier ProteinsCell Cycle ProteinsCluster AnalysisDNA-Binding ProteinsEpigenomicsGene Expression Regulation, FungalModels, MolecularNuclear ProteinsProtein BindingProtein ConformationProtein DomainsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsTranscription Factor TFIIDCarrier ProteinsCell Cycle ProteinsDNA-Binding ProteinsINO80 complex, S cerevisiaeNuclear ProteinsRSC complex, S cerevisiaeSaccharomyces cerevisiae ProteinsSTH1 protein, S cerevisiaeTAF14 protein, S cerevisiaeTranscription FactorsTranscription Factor TFIID

Identifiers

PMID32826896
PMCPMC7442819
OpenAlexW3080111102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.