Evidence map›Paper›PMID 32826776›Full record

ArticleMedical care2020

Tailored to Fit: How an Implementation Framework Can Support Pragmatic Pain Care Trial Adaptation for Diverse Veterans Affairs Clinical Settings.

Natalie Purcell, William C Becker, Kara A Zamora, Sarah L McGrath, Hildi J Hagedorn, Eva R Fabian, Nicole McCamish, Karen H Seal

Registry-linked trialOpen access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Medical care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04330365 (Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04330365 nacompletednot on this map

Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans

TypeinterventionalSponsorSan Francisco Veterans Affairs Medical CenterRan2020 to 2025Enrolled793ConditionsChronic PainArmsWhole Health Team (WHT) Intervention Arm, Primary Care Group Education (PC-GE) Intervention Arm, Usual Primary Care (UPC) Arm
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Natalie PurcellSan Francisco VA Health Care System.
William C BeckerVA Connecticut Healthcare System, West Haven.
Kara A ZamoraSan Francisco VA Health Care System.
Sarah L McGrathSan Francisco VA Health Care System.
Hildi J HagedornMinneapolis VA Health Care System.
Eva R FabianSan Francisco VA Health Care System.
Nicole McCamishSan Francisco VA Health Care System.
Karen H SealSan Francisco VA Health Care System.
San Francisco VA Health Care System · USMinneapolis VA Health Care System · USVA Connecticut Healthcare System · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Pain Management Collaboratory Coordinating Center (PMC3)U24AT009769 · NCCIH · YALE UNIVERSITY · PI WILLIAM C BECKER, Alicia Heapy · 2017 to 2026
$16.4M
Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Function and Quality of Life in VeteransUH3AT009765 · NCCIH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BECKER, WILLIAM C, SEAL, KAREN H · 2020 to 2024
$6.9M
Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in VeteransUG3AT009765 · NCCIH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BECKER, WILLIAM C, SEAL, KAREN H · 2017 to 2018
$1.5M
NCATS NIH HHS UL1 TR001863NCCIH NIH HHS U24 AT009769NCCIH NIH HHS UG3 AT009765NCCIH NIH HHS UH3 AT009765
6 · The paper itself

Abstract

backgroundVeterans Affairs (VA) has rolled out a holistic, multicomponent Whole Health care model nationwide, yet no pragmatic trials have been conducted in real-world clinical settings to compare its effectiveness against other evidence-based approaches for chronic pain management in veterans.

objectivesWe describe the adaptation of the first large pragmatic randomized controlled trial of the Whole Health model for chronic pain care for diverse VA clinical settings. RESEARCH

designInformed by the Promoting Action on Research Implementation in Health Systems implementation framework, we conducted qualitative semistructured interviews to obtain feedback on trial design from VA leadership, frontline clinicians, and veterans with chronic pain at 5 VA enrollment sites. Next, we convened in-person evidence-based quality improvement (EBQI) meetings with study stakeholders (including frontline clinicians and administrators) at each site to discuss study design; review interview themes; and identify site-specific barriers, facilitators, and approaches to implementation. Ethnographic observations from EBQI meetings provided additional insight into implementation strategies. SUBJECTS: Seventy-four veteran and VA staff stakeholders were interviewed; 71 stakeholders participated in EBQI meetings.

resultsAt each site, unique clinical contexts and varying resources for Whole Health and pain care delivery affected plans for trial implementation. We present examples of local adaptations that emerged through the formative evaluation process to facilitate implementation and yield a more pragmatic trial design.

conclusionsA systematic formative evaluation can facilitate engagement and buy-in of study stakeholders. Locally tailored pragmatic implementation strategies may improve the likelihood of successful trial execution as well as future implementation of evidence-based pain care approaches in real-world clinical settings.

Indexed as

Chronic PainIntegrative MedicineResearch DesignUnited States Department of Veterans AffairsAnthropology, CulturalAttitude of Health PersonnelEvidence-Based MedicineHumansInterviews as TopicMulticenter Studies as TopicPatient SelectionPragmatic Clinical Trials as TopicQuality ImprovementUnited StatesVeteransVeterans Health

Identifiers

PMID32826776
PMCPMC7444583
OpenAlexW3081419188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.