Evidence map›Paper›PMID 32826152›Full record

ArticleJournal of vascular and interventional radiology : JVIR2020

Three-Dimensional Augmented Reality Visualization Informs Locoregional Therapy in a Translational Model of Hepatocellular Carcinoma.

Brian J Park, Nicholas R Perkons, Enri Profka, Omar Johnson, Christopher Morley, Scott Appel, Gregory J Nadolski, Stephen J Hunt, Terence P Gade

Open access · greenAbstract read
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Augmented Reality Demonstration Survey Results From a Veteran Affairs Medical Center.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Brian J ParkDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 646 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104. Electronic address: bjinwoopark@gmail.com.
Nicholas R PerkonsDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 646 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104.
Enri ProfkaDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 646 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104.
Omar JohnsonDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 646 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104.
Christopher MorleyMedivis, Brooklyn, New York.
Scott AppelDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 646 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104.
Gregory J NadolskiDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 646 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104.
Stephen J HuntDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 646 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104.
Terence P GadeDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, 646 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104.
University of Pennsylvania · US

Funding

RESEARCH TRACK RADIOLOGY RESIDENCYT32EB004311 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Terence P Gade, Misun Hwang · 2005 to 2026
$4.5M
NIBIB NIH HHS T32 EB004311
6 · The paper itself

Abstract

purposeTo evaluate the utility of visualizing preprocedural MR images in 3-dimensional (3D) space using augmented reality (AR) before transarterial embolization of hepatocellular carcinoma (HCC) in a preclinical model. MATERIALS AND

methodsA total of 28 rats with diethylnitrosamine-induced HCCs > 5 mm treated with embolization were included in a prospective study. In 12 rats, 3D AR visualization of preprocedural MR images was performed before embolization. Procedural metrics including catheterization time and radiation exposure were compared vs a prospective cohort of 16 rats in which embolization was performed without AR. An additional cohort of 15 retrospective cases was identified and combined with the prospective control cohort (n = 31) to improve statistical power.

resultsA 37% reduction in fluoroscopy time, from 11.7 min to 7.4 minutes, was observed with AR when compared prospectively, which did not reach statistical significance (P = .12); however, when compared with combined prospective and retrospective controls, the reduction in fluoroscopy time from 14.1 min to 7.4 minutes (48%) was significant (P = .01). A 27% reduction in total catheterization time, from 42.7 minutes to 31.0 minutes, was also observed with AR when compared prospectively, which did not reach statistical significance (P = .11). No significant differences were seen in dose-area product or air kerma prospectively.

conclusionsThree-dimensional AR visualization of preprocedural imaging may aid in the reduction of procedural metrics in a preclinical model of transarterial embolization. These data support the need for further studies to evaluate the potential of AR in endovascular oncologic interventions.

Indexed as

Augmented RealityEmbolization, TherapeuticHolographyMagnetic Resonance ImagingAcrylic ResinsAnimalsCarcinoma, HepatocellularDiethylnitrosamineFemaleFluoroscopyGelatinLiver Neoplasms, ExperimentalMalePredictive Value of TestsRadiation DosageRadiation ExposureAcrylic ResinsDiethylnitrosamineGelatintrisacryl gelatin microspheres

Identifiers

PMID32826152
PMCPMC7541417
OpenAlexW3059005384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.