Evidence map›Paper›PMID 32825963›Full record

ReviewPathology, research and practice2020

Pathologic features of COVID-19: A concise review.

Mohammadreza Tabary, Shaghayegh Khanmohammadi, Farnaz Araghi, Sahar Dadkhahfar, Seyed Mohammad Tavangar

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Pathology, research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05185700 (Post Covid 19 Syndrome), which is not on this map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05185700 unknown statusnot on this mapstarted 2022, after this paper: background citation

Post Covid 19 Syndrome

TypeobservationalSponsorAssiut UniversityRan2022 to 2023Enrolled180ConditionsCOVID-19Armspost covid 19 symtoms
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Is COVID-19 Infection A Risk Factor for Intubation-Related Acquired Airway Stenosis?Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. SARS-CoV-2 RNA detection in Formalin-Fixed Paraffin-Embedded (FFPE) tissue by droplet digital PCR (ddPCR).Clinica chimica acta; international journal of clinical chemistry · 2022
    Article
  19. Article
  20. COVID-related hospitalization, intensive care treatment, and all-cause mortality in patients with psychosis and treated with clozapine.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mohammadreza TabaryExperimental Medicine Research Center, Tehran University of Medical Center, Tehran, Iran.
Shaghayegh KhanmohammadiSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Farnaz AraghiSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sahar DadkhahfarSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Mohammad TavangarDepartment of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: tavangar@ams.ac.ir.
Tehran University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), first appeared in December 2019, in Wuhan, China and evolved into a pandemic. As Angiotensin-Converting Enzyme 2 (ACE2) is one of the potential target receptors for SARS-CoV-2 in human body, which is expressed in different tissues, multiple organs might become affected. In the initial phase of the current pandemic, a handful of post-mortem case-series revealed COVID-19-related pathological changes in various organs. Although pathological examination is not a feasible method of diagnosis, it can elucidate pathological changes, pathogenesis of the disease, and the cause of death in COVID-19 cases. Herein, we thoroughly reviewed multiple organs including lung, gastrointestinal tract, liver, kidney, skin, heart, blood, spleen, lymph nodes, brain, blood vessels, and placenta in terms of COVID-19-related pathological alterations. Also, these findings were compared with SARS and MERS infection, wherever applicable. We found a diverse range of pathological changes, some of which resemble those found in SARS and MERS.

Indexed as

Angiotensin-Converting Enzyme 2BetacoronavirusChinaCoronavirus InfectionsCOVID-19HumansLungPandemicsPeptidyl-Dipeptidase APneumonia, ViralSARS-CoV-2ACE2 protein, humanAngiotensin-Converting Enzyme 2Peptidyl-Dipeptidase ACOVID-19HistopathologyPathologySARS-CoV-2

Identifiers

PMID32825963
PMCPMC7334952
OpenAlexW3038368915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.