ArticleRadiation oncology (London, England)2020
Treatment plan quality during online adaptive re-planning.
Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 56 citations in OpenAlex.
- Operating procedures, risk management and challenges during implementation of adaptive and non-adaptive MR-guided radiotherapy: 1-year single-center experience.Radiation oncology (London, England) · 2021Trial
- Topology-preserved transformer-based CBCT-CT registration via normalized gradient field guidance for nasopharyngeal carcinoma.iScience · 2026Article
- Longitudinal radiomics of liver metastases during magnetic resonance-guided radiotherapy.Physics and imaging in radiation oncology · 2026Article
- Dosimetric impact of daily MR-guided adaptive radiotherapy across different anatomical sites.Irish journal of medical science · 2026Article
- Evaluating the role of plan complexity metrics in online adaptive radiotherapy for pancreatic cancer patients.Medical physics · 2026Article
- Comparison of gantry-less magnetic resonance guided proton therapy with photon therapy for hepatocellular carcinoma patients.Physics and imaging in radiation oncology · 2026Article
- A deep-learning framework for the prediction of the type of adaptive strategy of MR-guided prostate radiotherapy.Journal of applied clinical medical physics · 2026Article
- Apparent diffusion coefficient as a quantitative biomarker for prostate cancer treatment response on a 1.5 Tesla magnetic resonance-linear accelerator: Impact of image registration and acquisition type.Physics and imaging in radiation oncology · 2025Article
- Evaluation of clinical and volumetric outcomes following adaptive gamma knife radiosurgery for brain metastases.Journal of neuro-oncology · 2025Article
- Evaluation of intra-fractional CBCT image quality using different megavoltage beam sizes and imaging conditions in a phantom study.Scientific reports · 2025Article
- Assessing Dosimetric Benefits of Cone Beam Computed Tomography-Guided Online Adaptive Radiation Treatment Frequencies for Lung Cancer.Advances in radiation oncology · 2025Article
- Geometric and dosimetric evaluation for breast and regional nodal auto-segmentation structures.Journal of applied clinical medical physics · 2024Article
- Evaluating the effect of higher Monte Carlo statistical uncertainties on accumulated doses after daily adaptive fractionated radiotherapy in prostate cancer.Physics and imaging in radiation oncology · 2024Article
- Optimization of treatment workflow for 0.35T MR-Linac system.Journal of applied clinical medical physics · 2024Article
- Measurement and Incorporation of Laryngeal Motion Using cine-MRI on an MR-Linear Accelerator to Generate Radiation Therapy Plans for Early-stage Squamous Cell Cancers of the Glottis.Advances in radiation oncology · 2024Article
- Full daily re-optimization improves plan quality during online adaptive radiotherapy.Physics and imaging in radiation oncology · 2024Article
- Review and recommendations on deformable image registration uncertainties for radiotherapy applications.Physics in medicine and biology · 2023Review
- Patient-specific quality assurance strategies for synthetic computed tomography in magnetic resonance-only radiotherapy of the abdomen.Physics and imaging in radiation oncology · 2023Article
- Synthetic computed tomography for low-field magnetic resonance-only radiotherapy in head-and-neck cancer using residual vision transformers.Physics and imaging in radiation oncology · 2023Article
- An independent Monte Carlo-based IMRT QA tool for a 0.35 T MRI-guided linear accelerator.Journal of applied clinical medical physics · 2023Article
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
Abstract
backgroundOnline adaptive radiotherapy is intended to prevent plan degradation caused by inter-fractional tumor volume and shape changes, but time limitations make online re-planning challenging. The aim of this study was to compare the quality of online-adapted plans to their respective reference treatment plans.
methodsFifty-two patients treated on a ViewRay MRIdian Linac were included in this retrospective study. In total 238 online-adapted plans were analyzed, which were optimized with either changing of the segment weights (n = 85) or full re-optimization (n = 153). Five different treatment sites were evaluated: prostate, abdomen, liver, lung and pelvis. Dosimetric parameters of gross tumor volume (GTV), planning target volume (PTV), 2 cm ring around the PTV and organs at risk (OARs) were considered. The Wilcoxon signed-rank test was used to assess differences between online-adapted and reference treatment plans, p < 0.05 was considered significant.
resultsThe average duration of the online adaptation, consisting of contour editing, plan optimization and quality assurance (QA), was 24 ± 6 min. The GTV was slightly larger (average ± SD: 1.9% ± 9.0%) in the adapted plans than in the reference plans (p < 0.001). GTV-D
conclusionsDosimetric quality of online-adapted plans was comparable to reference treatment plans and OAR dose was either comparable or decreased, depending on treatment site. However, dose spillage was slightly increased.
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