Evidence map›Paper›PMID 32825819›Full record

ArticleRespiratory research2020

Laryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study.

Julia Sanchez, Desiree M Schumann, Meropi Karakioulaki, Eleni Papakonstantinou, Frank Rassouli, Matthias Frasnelli, Martin Brutsche, Michael Tamm, Daiana Stolz

Open access · goldAbstract readLetterMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Julia SanchezClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
Desiree M SchumannClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
Meropi KarakioulakiClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
Eleni PapakonstantinouClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
Frank RassouliDepartment of Pneumology, Kantonsspital St. Gallen, Rorschacherstrasse 95, St. Gallen, CH-9001, Switzerland.
Matthias FrasnelliDepartment of Pneumology, Kantonsspital Graubünden, Loestrasse 170, Chur, CH-7000, Chur, Switzerland.
Martin BrutscheDepartment of Pneumology, Kantonsspital St. Gallen, Rorschacherstrasse 95, St. Gallen, CH-9001, Switzerland.
Michael TammClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
Daiana StolzClinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland. Daiana.Stolz@usb.ch.
University Hospital of Basel · CHKantonsspital St. Gallen · CHKantonsspital Graubünden · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PP00-P3_128412/1
6 · The paper itself

Abstract

Reflux of gastric content has been associated with recurrent exacerbations of chronic obstructive pulmonary disease (COPD). We aimed to assess the prevalence of laryngopharyngeal reflux (LPR) in COPD and if LPR is a contributing factor to clinically relevant outcomes in COPD. We evaluated a total of 193 COPD patients (GOLD I-IV) with a 24-h laryngo-pharyngeal pΗ-monitor. LPR was observed in 65.8% of COPD patients and it was not significantly associated with clinically relevant outcomes of COPD. Treatment with PPI significantly decreased the upright RYAN score (p = 0.047) without improving lung function. Furthermore, the presence or severity of LPR cannot be diagnosed based solely on symptoms and questionnaires.

Indexed as

Surveys and QuestionnairesAgedFemaleFollow-Up StudiesHumansLaryngopharyngeal RefluxLongitudinal StudiesMaleMiddle AgedProspective StudiesPulmonary Disease, Chronic ObstructiveRespiratory Function TestsChronic obstructive pulmonary diseaseGastroesophageal refluxLaryngopharyngeal refluxProton pump inhibitor therapyRYAN score

Identifiers

PMID32825819
PMCPMC7441701
OpenAlexW3080611869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.