ArticleDiagnostics (Basel, Switzerland)2020
The Model for Early COvid-19 Recognition (MECOR) Score: A Proof-of-Concept for a Simple and Low-Cost Tool to Recognize a Possible Viral Etiology in Community-Acquired Pneumonia Patients during COVID-19 Outbreak.
Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 42 citations in OpenAlex.
- Predictive model for coronavirus disease 2019 severity based on blood biomarkers: a retrospective study.Frontiers in medicine · 2025Article
- From diversity to disease: unravelling the role of enteric glial cells.Frontiers in immunology · 2024Review
- Extracting relevant predictive variables for COVID-19 severity prognosis: An exhaustive comparison of feature selection techniques.PloS one · 2023Article
- Pilot study to evaluate hypercoagulation and inflammation using rotational thromboelastometry and calprotectin in COVID-19 patients.PloS one · 2023Article
- Predictors of Hepatocellular Carcinoma Early Recurrence in Patients Treated with Surgical Resection or Ablation Treatment: A Single-Center Experience.Diagnostics (Basel, Switzerland) · 2022Article
- From Bench to Bedside: Clinical and Biomedical Investigations on Hepatitis C Virus (HCV) Genotypes and Risk Factors for Albuminuria.Bioengineering (Basel, Switzerland) · 2022Article
- Nonalcoholic Fatty Liver Disease and Altered Neuropsychological Functions in Patients with Subcortical Vascular Dementia.Journal of personalized medicine · 2022Article
- The Impact of Serum Albumin Levels on COVID-19 Mortality.Infectious disease reports · 2022Article
- Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases.International journal of molecular sciences · 2022Review
- A Dispatch Screening Tool to Identify Patients at High Risk for COVID-19 in the Prehospital Setting.The western journal of emergency medicine · 2021Article
- Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation-Experience of a Low Volume Ablation Centre.Medicina (Kaunas, Lithuania) · 2021Article
- Calprotectin and SARS-CoV-2: A Brief-Report of the Current Literature.Healthcare (Basel, Switzerland) · 2021Article
- Role of Laboratory Medicine in SARS-CoV-2 Diagnostics. Lessons Learned from a Pandemic.Healthcare (Basel, Switzerland) · 2021Review
- SalivaSTAT: Direct-PCR and Pooling of Saliva Samples Collected in Healthcare and Community Setting for SARS-CoV-2 Mass Surveillance.Diagnostics (Basel, Switzerland) · 2021Article
- The E/e' Ratio-Role in Risk Stratification of Acute Heart Failure with Preserved Ejection Fraction.Medicina (Kaunas, Lithuania) · 2021Article
- Risk Score for Predicting In-Hospital Mortality in COVID-19 (RIM Score).Diagnostics (Basel, Switzerland) · 2021Article
- Elevated Monocyte to Lymphocyte Ratio and Increased Mortality among Patients with Chronic Kidney Disease Hospitalized for COVID-19.Journal of personalized medicine · 2021Article
- White Blood Cells and Severe COVID-19: A Mendelian Randomization Study.Journal of personalized medicine · 2021Article
- COVID-19 and Diagnostic Testing for SARS-CoV-2 by RT-qPCR-Facts and Fallacies.International journal of molecular sciences · 2021Article
- Diagnosis of COVID-19 in Patients with Negative Nasopharyngeal Swabs: Reliability of Radiological and Clinical Diagnosis and Accuracy Versus Serology.Diagnostics (Basel, Switzerland) · 2021Article
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Authors and funding
23 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aims to assess the peripheral blood cell count "signature" of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) to discriminate promptly between COronaVIrus Disease 19 (COVID-19) and community-acquired pneumonia (CAP). We designed a retrospective case-control study, enrolling 525 patients (283 COVID-19 and 242 with CAP). All patients had a fever and at least one of the following signs: cough, chest pain, or dyspnea. We excluded patients treated with immunosuppressants, steroids, or affected by diseases known to modify blood cell count. COVID-19 patients showed a significant reduction in white blood cells (neutrophils, lymphocytes, monocytes, eosinophils) and platelets. We studied these parameters univariately, combined the significant ones in a multivariate model (AUROC 0.86, Nagelkerke PSEUDO-R2 0.5, Hosmer-Lemeshow
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