SynthesisInternational journal of environmental research and public health2020
Maggot Therapy in Wound Healing: A Systematic Review.
Synthesis in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Comparison of healing effectiveness of different debridement approaches for diabetic foot ulcers: a network meta-analysis of randomized controlled trials.Frontiers in public health · 2023Pooled it
- An integrative review of wound healing: anatomy, molecular mediators, and indigenous therapies.Molecular biology reports · 2026Review
- Insecticidal and immunotoxic actions of 2-octenoic acid in the green bottle fly Lucilia sericata (Diptera: Calliphoridae).Medical and veterinary entomology · 2026Article
- Determinants of nurses' knowledge on maggot debridement therapy: influence of demographic, professional, and educational factors in a Malaysian teaching hospital.BMC complementary medicine and therapies · 2026Article
- Morphometric Evaluation of Maggot Debridement Therapy on Healing Outcomes in Chronic Wounds.Journal of clinical medicine · 2026Article
- Neglected Myiasis Wound Presenting With Septic Shock: A Case Report.Clinical case reports · 2026Article
- Successful treatment of tuberculous wounds using Maggot Debridement Therapy (MDT): A case report.IDCases · 2026Article
- Efficacy of Larval Therapy for Wounds: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Expanding access to maggot containment dressings through redesign and innovation.International wound journal · 2025Article
- Eat and heal. Past, present and future of maggot debridement therapy: a narrative review.Le infezioni in medicina · 2025Article
- Maggots in Medicine: A Narrative Review Discussing the Barriers to Maggot Debridement Therapy and Its Utilisation in the Treatment of Chronic Wounds.Journal of clinical medicine · 2024Review
- Stability of Fly Maggot Peptides and Its Alleviating Effect on Lipopolysaccharide Combined with Hemocoagulase Oxidative Stress in Arbor Acres Chicks.Veterinary sciences · 2024Article
- Synergistic Treatment of Infected Burn Wound Utilizing Maggot Debridement and Acellular Fish Skin Grafting-A Case Report.Journal of burn care & research : official publication of the American Burn Association · 2024Article
- Protective effects of the bioactive peptide from maggots against skin flap ischemia‒reperfusion injury in rats.Heliyon · 2024Article
- Exploring the potential of naturally occurring antimicrobials for managing orthopedic-device-related infections.Journal of bone and joint infection · 2024Review
- Variables Associated with Attitudes toward Biodebridement UsingHealthcare (Basel, Switzerland) · 2023Article
- Pushing the frontiers in the fight against antimicrobial resistance: the potential of fecal and maggot therapies.Future science OA · 2023Review
- Larval Wound Therapy: Possibilities and Potential Limitations-A Literature Review.Journal of clinical medicine · 2023Review
- Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected withPharmaceutics · 2023Review
- Defensins ofInternational journal of environmental research and public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is estimated that 2% of the population in developing countries suffer from a chronic wound, making it a hidden phenomenon that is increasing as populations age. The ease of access to maggot therapy has made it increasingly attractive for implementation. This study aimed to explore the effectiveness of maggot therapy as compared to hydrogel dressings in the healing of chronic wounds.
methodsAn electronic literature search until October 2019 was performed using Medline, Embase, and Cumulative Index of Nursing and Allied Health Literature. The eligibility criteria were chronic wound patients with an intervention that involved a comparison of any maggot species with hydrogel dressings.
resultsThe full text of five studies, involving 580 patients with chronic wounds, was retrieved. Four studies used the Lucilia sericata species. The maggot therapy facilitated faster and more effective debridement of non-viable tissue. It enabled faster development of granulation tissue and increased reduction in the wound surface area compared to hydrogel dressings. Maggot therapy had no effect on disinfection or complete healing rate for the wound.
conclusionMaggot therapy should be considered for faster wound debridement, granulation tissue development, and wound surface area reduction as well as in surgical contraindications. This review can be used as a guide to assist clinicians in identifying patients who may benefit from maggot therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.