Evidence map›Paper›PMID 32825726›Full record

ArticleMicromachines2020

A Probeless Capacitive Biosensor for Direct Detection of Amyloid Beta 1-42 in Human Serum Based on an Interdigitated Chain-Shaped Electrode.

Hien T Ngoc Le, Jinsoo Park, Sungbo Cho

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hien T Ngoc LeDepartment of Electronic Engineering, Gachon University, Seongnam-si, Gyeonggi-do 13120, Korea.ORCID 0000-0001-9266-2447
Jinsoo ParkDepartment of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Korea.ORCID 0000-0001-6806-3209
Sungbo ChoDepartment of Electronic Engineering, Gachon University, Seongnam-si, Gyeonggi-do 13120, Korea.ORCID 0000-0003-3839-6410
Gachon University · KR

Funding

National Research Foundation of Korea NRF 2017R1D1A1A09000712, 2018M3A9F1023690, and 2018M3A9F1023691
6 · The paper itself

Abstract

Amyloid beta (aβ) 1-42, a peptide that is 1-42 amino acids long, is a major component of senile plaques in the brains of patients with Alzheimer's disease. Aβ detection has become an essential antecedence to predict the declining mental abilities of patients. In this paper, a probeless capacitive biosensor for the non-Faradaic detection of aβ 1-42 peptide was developed by immobilizing a specific anti-aβ antibody onto a self-assembled monolayer functionalized interdigitated chain-shaped electrode (anti-aβ/SAM/ICE). The novelty and difference of this article from previous studies is the direct detection of aβ peptide with no redox probe ((Fe(CN)

Indexed as

amyloid-β 1-42 peptideanti-aβ antibodycapacitive biosensorelectrochemical impedance spectroscopyinterdigitated chain-shaped electrodeself-assembled monolayer

Identifiers

PMID32825726
PMCPMC7569882
OpenAlexW3080289936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.