Evidence map›Paper›PMID 32825702›Full record

ArticleVaccines2020

Evaluation of a Pseudotyped Virus Neutralisation Test for the Measurement of Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection.

Rebecca Kinsley, Stéphane Pronost, Manuelle De Bock, Nigel Temperton, Janet M Daly, Romain Paillot, Simon Scott

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Rebecca KinsleyViral Pseudotype Unit (VPU), Medway School of Pharmacy, Universities of Kent & Greenwich, Chatham Maritime ME4 4TB, UK.
Stéphane PronostLABÉO Frank Duncombe, 1 route de Rosel, 14053 Caen CEDEX 4, France.
Manuelle De BockElanco Animal Health, Plantin en Moretuslei, B-2018 Antwerpen, Belgium.
Nigel TempertonViral Pseudotype Unit (VPU), Medway School of Pharmacy, Universities of Kent & Greenwich, Chatham Maritime ME4 4TB, UK.ORCID 0000-0002-7978-3815
Janet M DalySchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington LE12 5RD, UK.ORCID 0000-0002-1912-4500
Romain PaillotLABÉO Frank Duncombe, 1 route de Rosel, 14053 Caen CEDEX 4, France.ORCID 0000-0003-3081-2037
Simon ScottViral Pseudotype Unit (VPU), Medway School of Pharmacy, Universities of Kent & Greenwich, Chatham Maritime ME4 4TB, UK.ORCID 0000-0002-8290-0461
Medway School of Pharmacy · GBAnimal Health Trust · GBNormandie Université · FRUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Equine influenza is a major respiratory disease of horses that is largely controlled by vaccination in some equine populations. Virus-neutralising antibodies, the mainstay of the protective immune response, are problematic in assaying for equine influenza virus, as most strains do not replicate efficiently in cell culture. Surrogate measures of protective antibody responses include the haemagglutination inhibition (HI) test and single radial haemolysis (SRH) assay. For this study, a pseudotyped virus, bearing an envelope containing the haemagglutinin (HA) from the Florida clade 2 equine influenza virus strain A/equine/Richmond/1/07 (H3N8), was generated to measure HA-specific neutralising antibodies in serum samples (

Indexed as

equine influenzahorsepseudotype virusvaccine

Identifiers

PMID32825702
PMCPMC7565038
OpenAlexW3081037232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.