Evidence map›Paper›PMID 32825664›Full record

ArticleCells2020

Molecular Genetics and Functional Analysis Implicate

Sonika Rathi, Ian Danford, Harini V Gudiseva, Lana Verkuil, Maxwell Pistilli, Sushma Vishwakarma, Inderjeet Kaur, Tarjani Dave, Joan M O'Brien, Venkata R M Chavali

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  7. SH-SY5Y human neuronal cells with mutations of theBiochemistry and biophysics reports · 2024
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  9. Analysis ofInternational journal of ophthalmology · 2024
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Sonika RathiScheie Eye Institute, Department of Ophthalmology, Philadelphia, PA 19104, USA.
Ian DanfordScheie Eye Institute, Department of Ophthalmology, Philadelphia, PA 19104, USA.
Harini V GudisevaScheie Eye Institute, Department of Ophthalmology, Philadelphia, PA 19104, USA.
Lana VerkuilScheie Eye Institute, Department of Ophthalmology, Philadelphia, PA 19104, USA.
Maxwell PistilliScheie Eye Institute, Department of Ophthalmology, Philadelphia, PA 19104, USA.
Sushma VishwakarmaProf Brien Holden Eye Research Centre, L. V. Prasad Eye Institute, Hyderabad, Telangana 500034, India.
Inderjeet KaurProf Brien Holden Eye Research Centre, L. V. Prasad Eye Institute, Hyderabad, Telangana 500034, India.ORCID 0000-0003-3660-5039
Tarjani DaveProf Brien Holden Eye Research Centre, L. V. Prasad Eye Institute, Hyderabad, Telangana 500034, India.
Joan M O'BrienScheie Eye Institute, Department of Ophthalmology, Philadelphia, PA 19104, USA.
Venkata R M ChavaliScheie Eye Institute, Department of Ophthalmology, Philadelphia, PA 19104, USA.ORCID 0000-0003-3439-3490
Penn Presbyterian Medical Center · USL V Prasad Eye Institute · IN

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI CLAIRE H MITCHELL · 1985 to 2026
$19.5M
Primary Open Angle African-American Glaucoma Genetics Study RenewalR01EY023557 · NEI · UNIVERSITY OF PENNSYLVANIA · PI O'BRIEN, JOAN M · 2014 to 2025
$18.1M
Deciphering the role of lipid metabolism pathways in the RPE and their implications for AMDR21EY028273 · NEI · UNIVERSITY OF PENNSYLVANIA · PI CHAVALI, VENKATA RAMANA MURTHY · 2018 to 2019
$443k
NEI NIH HHS HHSN263201200001CNEI NIH HHS P30 EY001583NEI NIH HHS R01 EY023557NEI NIH HHS R21 EY028273
6 · The paper itself

Abstract

The genes in the 9p21 locus (

Indexed as

AdultCyclin-Dependent Kinase Inhibitor p15Genetic Predisposition to DiseaseGlaucoma, Open-AngleHumansMolecular BiologyCDKN2B protein, humanCyclin-Dependent Kinase Inhibitor p15African AmericansCDKN2B-AS1Primary open-angle glaucoma (POAG)senescencetrabecular meshwork cells

Identifiers

PMID32825664
PMCPMC7564117
OpenAlexW3080525018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.