ArticleDiagnostics (Basel, Switzerland)2020
Red Blood Cell Distribution Width (RDW) Predicts COVID-19 Severity: A Prospective, Observational Study from the Cincinnati SARS-CoV-2 Emergency Department Cohort.
Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- Role of red blood cell distribution width, as a prognostic indicator in COVID-19: A systematic review and meta-analysis.Reviews in medical virology · 2022Pooled it
- Association between red blood cell distribution width and mortality and severity among patients with COVID-19: A systematic review and meta-analysis.Journal of medical virology · 2021Pooled it
- Red Cell Distribution Width (RDW), Platelets and Platelet Index MPV/PLT Ratio as Specific Time Point Predictive Variables of Survival Outcomes in COVID-19 Hospitalized Patients.Journal of clinical medicine · 2025Article
- Article
- Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19.Life (Basel, Switzerland) · 2024Article
- Increased red cell distribution width predicts mortality in COVID-19 patients admitted to a Dutch intensive care unit.Acute and critical care · 2024Article
- Association between red cell distribution width to albumin ratio and acute kidney injury in patients with sepsis: a MIMIC population-based study.International urology and nephrology · 2023Article
- Changes in Hematological and Hemorheological Parameters Following Mild COVID-19: A 4-Month Follow-Up Study.Hematology reports · 2023Article
- Association of red blood cell distribution width with hospital admission and in-hospital mortality across all-cause adult emergency department visits.JAMIA open · 2023Article
- Paediatric COVID-19 Outcomes: Haematology Parameters, Mortality Rates, and Hospitalization Duration.Children (Basel, Switzerland) · 2023Article
- A Survey of COVID-19 Diagnosis Using Routine Blood Tests with the Aid of Artificial Intelligence Techniques.Diagnostics (Basel, Switzerland) · 2023Review
- Serial Changes in Blood-Cell-Count-Derived and CRP-Derived Inflammatory Indices of COVID-19 Patients.Diagnostics (Basel, Switzerland) · 2023Article
- Plasma 25(OH)D Level is Associated with the Nucleic Acid Negative Conversion Time of COVID-19 Patients: An Exploratory Study.Infection and drug resistance · 2023Article
- Baseline and early changes in laboratory parameters predict disease severity and fatal outcomes in COVID-19 patients.Frontiers in public health · 2023Article
- Simple hemogram to support the decision-making of COVID-19 diagnosis using clusters analysis with self-organizing maps neural network.Soft computing · 2023Article
- COVID-19 screening with digital holographic microscopy using intra-patient probability functions of spatio-temporal bio-optical attributes.Biomedical optics express · 2022Article
- Molnupiravir as an Early Treatment for COVID-19: A Real Life Study.Pathogens (Basel, Switzerland) · 2022Article
- Clinical outcomes at medium-term follow-up of COVID-19.The journal of the Royal College of Physicians of Edinburgh · 2022Article
- RDW shows prognostic potential in hospitalized patients with COVID-19.Journal of medical virology · 2022Article
- Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
Since previous evidence has demonstrated that red blood cell distribution width (RDW) may be a useful prognostic parameter in many critical illnesses and infectious diseases, we investigated the utility of RDW for monitoring patients with coronavirus disease 2019 (COVID-19). The study population consisted of 49 COVID-19 patients, including 16 (32.6%) with severe illness, 12 (24.5%) with severe acute kidney injury (AKI), and 8 (16.3%) requiring renal replacement therapy (RRT). The predictive value of blood tests, performed during emergency department evaluation, was then addressed. A progressive increase of RDW was observed with advancing COVID-19 severity. The area under the curve (AUC) of RDW was 0.73 for predicting severe illness, 0.80 for severe AKI, and 0.83 for RRT, respectively. In multivariate analysis, elevated RDW was associated with 9-fold and 16-fold increased odds of severe COVID-19 and AKI, respectively. The results of this study suggest that RDW should be part of routine laboratory assessment and monitoring of COVID-19.
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Registered trials
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