Evidence map›Paper›PMID 32825521›Full record

ArticleInternational journal of molecular sciences2020

Adenovirus-Mediated

Madalina Dumitrescu, Violeta Georgeta Trusca, Lorand Savu, Ioana Georgeta Stancu, Attila Cristian Ratiu, Maya Simionescu, Anca Violeta Gafencu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Enhanced Suppression of Immune Cells In Vitro by MSC Overexpressing FasL.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Madalina DumitrescuGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology "N. Simionescu", 8, B.P. Hasdeu Street, 050568 Bucharest, Romania.
Violeta Georgeta TruscaGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology "N. Simionescu", 8, B.P. Hasdeu Street, 050568 Bucharest, Romania.
Lorand SavuMolecular Biology Department, Genetic Lab, 9 Căpitan Nicolae Drossu Street, 012071 Bucharest, Romania.
Ioana Georgeta StancuMolecular Biology Department, Genetic Lab, 9 Căpitan Nicolae Drossu Street, 012071 Bucharest, Romania.
Attila Cristian RatiuMolecular Biology Department, Genetic Lab, 9 Căpitan Nicolae Drossu Street, 012071 Bucharest, Romania.
Maya SimionescuGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology "N. Simionescu", 8, B.P. Hasdeu Street, 050568 Bucharest, Romania.
Anca Violeta GafencuGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology "N. Simionescu", 8, B.P. Hasdeu Street, 050568 Bucharest, Romania.ORCID 0000-0002-1290-1346
University of Bucharest · RO

Funding

European Regional Development Fund through the Competitiveness Operational Program 2014-2020 POC-A.1-A.1.1.4-E-2015, ID: P_37_668Romanian Academy Ro
6 · The paper itself

Abstract

Fas ligand (First apoptosis signal ligand, FasL, also known as CD95L) is the common executioner of apoptosis within the tumor necrosis factor (TNF) superfamily. We aimed to induce functional FasL expression in transduced cells using an adenovirus vector, which has the advantage of strong and transient induction of the gene included in the adenoviral genome. Here, we report that the adenovirus carrying a truncated

Indexed as

Gene Transfer Techniques3' Untranslated RegionsAdenoviridaeAnimalsApoptosisCattleCoculture TechniquesEndothelial CellsFas Ligand ProteinGreen Fluorescent ProteinsHEK293 CellsHepatocytesHumansIntronsMiceMice, Inbred BALB C3' Untranslated RegionsFas Ligand ProteinFasl protein, mouseGreen Fluorescent ProteinsRecombinant ProteinsadenovirusapoptosiscDNAFasLminigene

Identifiers

PMID32825521
PMCPMC7504687
OpenAlexW3068587951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.