Evidence map›Paper›PMID 32825480›Full record

ArticleBiomolecules2020

Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters.

Miljan N M Milunović, Oleg Palamarciuc, Angela Sirbu, Sergiu Shova, Dan Dumitrescu, Dana Dvoranová, Peter Rapta, Tatsiana V Petrasheuskaya, Eva A Enyedy, Gabriella Spengler and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. A novel water-soluble thiosemicarbazone Schiff base ligand and its complexes as potential anticancer agents and cellular fluorescence imaging.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 5 countries.

Miljan N M MilunovićInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Strasse 42, A-1090 Vienna, Austria.
Oleg PalamarciucDepartment of Chemistry, Moldova State University, A. Mateevici Street 60, MD-2009 Chisinau, Moldova.
Angela SirbuDepartment of Chemistry, Moldova State University, A. Mateevici Street 60, MD-2009 Chisinau, Moldova.
Sergiu ShovaPetru Poni Institute of Macromolecular Chemistry, Laboratory of Inorganic Polymers, Aleea Grigore Ghica Voda, Nr. 41A, 700487 Iasi, Romania.
Dan DumitrescuElettra-Sincrotrone Trieste S.C.p.A, Strada Statale 14-km 163,5 in AREA Science Park, 34149 Basovizza, Trieste, Italy.
Dana DvoranováInstitute of Physical Chemistry and Chemical Physics, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinského 9, SK-81237 Bratislava, Slovakia.
Peter RaptaInstitute of Physical Chemistry and Chemical Physics, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinského 9, SK-81237 Bratislava, Slovakia.
Tatsiana V PetrasheuskayaDepartment of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
Eva A EnyedyDepartment of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
Gabriella SpenglerMTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
Marija IlicDepartment of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, A-1090 Vienna, Austria.
Harald H SitteInstitute of Pharmacology, Centre for Physiology and Pharmacology, Medical University of Vienna, A-1090 Vienna, Austria.
Gert LubecNeuroproteomics, Paracelsus Private Medical University, 5020 Salzburg, Austria.
Vladimir B ArionInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Strasse 42, A-1090 Vienna, Austria.
University of Szeged · HUUniversity of Vienna · ATMoldova State University · MDSlovak University of Technology in Bratislava · SKElettra-Sincrotrone Trieste S.C.p.A. · ITInstitutul de Chimie Macromoleculară Petru PoniMedical University of Vienna · ATParacelsus Medical University · AT

Funding

Austrian Science Fund (FWF grant no. P28223)
6 · The paper itself

Abstract

A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively charged trimethylammonium moiety ([H

Indexed as

AldehydesAntineoplastic AgentsCell LineCell ProliferationCoordination ComplexesCopperCrystallography, X-RayDrug Screening Assays, AntitumorHumansModels, MolecularMolecular StructureOrganic Cation Transport ProteinsThiosemicarbazonesAldehydesAntineoplastic AgentsCoordination ComplexesCopperOrganic Cation Transport Proteinssalicylaldehyde thiosemicarbazoneThiosemicarbazonescopper(II) complexescytotoxicityorganic cation transporters (OCT1–3), inhibitorsthiosemicarbazones

Identifiers

PMID32825480
PMCPMC7565988
OpenAlexW3058137391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.