Evidence map›Paper›PMID 32825417›Full record

ArticleMicroorganisms2020

Investigating Both Mucosal Immunity and Microbiota in Response to Gut Enteritis in Yellowtail Kingfish.

Thibault P R A Legrand, James W Wynne, Laura S Weyrich, Andrew P A Oxley

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Thibault P R A LegrandDepartment of Ecology and Evolution, School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0003-3386-1598
James W WynneCSIRO, Agriculture and Food, Hobart, TAS 7004, Australia.
Laura S WeyrichDepartment of Ecology and Evolution, School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.
Andrew P A OxleySchool of Life and Environmental Sciences, Faculty of Sciences Engineering and Built Environment, Deakin University, Waurn Ponds, VIC 3216, Australia.
Commonwealth Scientific and Industrial Research Organisation · AUDeakin University · AUPennsylvania State University · US

Funding

Australian Government, Department of Agriculture and Water Resources 2016-200.30Commonwealth Scientific and Industrial Research Organisation (CSIRO) Postgraduate Scholarship program Not applicableFisheries Research and Development Corporation RnD4Profit 14-01-027
6 · The paper itself

Abstract

The mucosal surfaces of fish play numerous roles including, but not limited to, protection against pathogens, nutrient digestion and absorption, excretion of nitrogenous wastes and osmotic regulation. During infection or disease, these surfaces act as the first line of defense, where the mucosal immune system interacts closely with the associated microbiota to maintain homeostasis. This study evaluated microbial changes across the gut and skin mucosal surfaces in yellowtail kingfish displaying signs of gut inflammation, as well as explored the host gene expression in these tissues in order to improve our understanding of the underlying mechanisms that contribute to the emergence of these conditions. For this, we obtained and analyzed 16S rDNA and transcriptomic (RNA-Seq) sequence data from the gut and skin mucosa of fish exhibiting different health states (i.e., healthy fish and fish at the early and late stages of enteritis). Both the gut and skin microbiota were perturbed by the disease. More specifically, the gastrointestinal microbiota of diseased fish was dominated by an uncultured

Indexed as

aquaculturefishguthealthimmunitymicrobiotamucosaskin

Identifiers

PMID32825417
PMCPMC7565911
OpenAlexW3072246308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.