ArticlePolymers2020
Influence of Hydroxyapatite Nanoparticles and Surface Plasma Treatment on Bioactivity of Polycaprolactone Nanofibers.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 29 citations in OpenAlex.
- Osteogenic differentiation by pre-osteoblasts is enhanced more on 3D-PRINTED poly-ɛ-caprolactone scaffolds coated with collagen and hydroxyapatite than on poly-ɛ-caprolactone/hydroxyapatite composite scaffolds coated with collagen.Journal of biomaterials applications · 2026Article
- Electrospun Poly(L-lactide-co-ε-caprolactone) Nanofibers with Hydroxyapatite Nanoparticles Mimic Cellular Interplay in Bone Regeneration.International journal of molecular sciences · 2025Article
- Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering.Science and technology of advanced materials · 2023Article
- Effect of PCL/nHAEA nanocomposite to osteo/odontogenic differentiation of dental pulp stem cells.BMC oral health · 2022Article
- Article
- Article
- Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering Applications.Bioengineering (Basel, Switzerland) · 2021Review
- Antibacterial Poly(ε-CL)/Hydroxyapatite Electrospun Fibers Reinforced by Poly(ε-CL)-International journal of molecular sciences · 2021Article
- Improved healing of critical-size femoral defect in osteoporosis rat models using 3D elastin/polycaprolactone/nHA scaffold in combination with mesenchymal stem cells.Journal of materials science. Materials in medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Nanofibers are well known as a beneficial type of structure for tissue engineering. As a result of the high acquisition cost of the natural polymers and their environmentally problematic treatment (toxic dissolution agents), artificial polymers seem to be the better choice for medical use. In the present study, polycaprolactone nano-sized fibrous structures were prepared by the electrospinning method. The impact of material morphology (random or parallelly oriented fibers versus continuous layer) and the presence of a fraction of hydroxyapatite nanoparticles on cell proliferation was tested. In addition, the effect of improving the material wettability by a low temperature argon discharge plasma treatment was evaluated, too. We have shown that both hydroxyapatite particles as well as plasma surface treatment are beneficial for the cell proliferation. The significant impact of both influences was evident during the first 48 h of the test: the hydroxyapatite particles in polycaprolactone fibers accelerated the proliferation by 10% compared to the control, and the plasma-treated ones enhanced proliferation by 30%.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.