ReviewVaccines2020
Are Vaccines the Solution for Methane Emissions from Ruminants? A Systematic Review.
Review in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Methane emissions in beef cattle: A review of measurements and mitigation strategies.Veterinary and animal science · 2026Review
- Detection and quantification of rumen methanogens using FApplied and environmental microbiology · 2026Article
- Serum as a surrogate for salivary IgG: comparison of antigen-specific serum and salivary IgG in sheep.Frontiers in immunology · 2026Article
- Improving Human Diets and Welfare through Using Herbivore-Based Foods: 2. Environmental Consequences and Mitigations.Animals : an open access journal from MDPI · 2024Review
- - Invited Review - Hydrogen production and hydrogen utilization in the rumen: key to mitigating enteric methane production.Animal bioscience · 2024Article
- A Longitudinal Study with a Laser Methane Detector (LMD) Highlighting Lactation Cycle-Related Differences in Methane Emissions from Dairy Cows.Animals : an open access journal from MDPI · 2023Article
- Galyean appreciation club review: a holistic perspective of the societal relevance of beef production and its impacts on climate change.Journal of animal science · 2023Article
- The evolving role of methanogenic archaea in mammalian microbiomes.Frontiers in microbiology · 2023Review
- Hydrogen and formate production and utilisation in the rumen and the human colon.Animal microbiome · 2022Review
- Alternative pathways for hydrogen sink originated from the ruminal fermentation of carbohydrates: Which microorganisms are involved in lowering methane emission?Animal microbiome · 2022Review
- Methane Emissions from Ruminants in Australia: Mitigation Potential and Applicability of Mitigation Strategies.Animals : an open access journal from MDPI · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ruminants produce considerable amounts of methane during their digestive process, which makes the livestock industry as one of the largest sources of anthropogenic greenhouse gases. To tackle this situation, several solutions have been proposed, including vaccination of ruminants against microorganisms responsible for methane synthesis in the rumen. In this review, we summarize the research done on this topic and describe the state of the art of this strategy. The different steps implied in this approach are described: experimental design, animal model (species, age), antigen (whole cells, cell parts, recombinant proteins, peptides), adjuvant (Freund's, Montanide, saponin, among others), vaccination schedule (booster intervals and numbers) and measurements of treatment success (immunoglobulin titers and/or effects on methanogens and methane production). Highlighting both the advances made and knowledge gaps in the use of vaccines to inhibit ruminant methanogen activity, this research review opens the door to future studies. This will enable improvements in the methodology and systemic approaches so as to ensure the success of this proposal for the sustainable mitigation of methane emission.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.