Evidence map›Paper›PMID 32825366›Full record

ArticleMolecules (Basel, Switzerland)2020

Phenylpiperazine 5,5-Dimethylhydantoin Derivatives as First Synthetic Inhibitors of Msr(A) Efflux Pump in

Karolina Witek, Gniewomir Latacz, Aneta Kaczor, Joanna Czekajewska, Ewa Żesławska, Anna Chudzik, Elżbieta Karczewska, Wojciech Nitek, Katarzyna Kieć-Kononowicz, Jadwiga Handzlik

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Karolina WitekDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Krakow, Poland.
Gniewomir LataczDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Krakow, Poland.ORCID 0000-0001-9247-2598
Aneta KaczorDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Krakow, Poland.
Joanna CzekajewskaDepartment of Pharmaceutical Microbiology, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Krakow, Poland.
Ewa ŻesławskaInstitute of Biology, Pedagogical University of Krakow, ul. Podchorążych 2, 30-084 Krakow, Poland.ORCID 0000-0003-1946-9370
Anna ChudzikDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Krakow, Poland.
Elżbieta KarczewskaDepartment of Pharmaceutical Microbiology, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Krakow, Poland.
Wojciech NitekFaculty of Chemistry, Jagiellonian University, ul. Gronostajowa 2, 30-387 Krakow, Poland.
Katarzyna Kieć-KononowiczDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Krakow, Poland.ORCID 0000-0002-6752-7443
Jadwiga HandzlikDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, ul. Medyczna 9, 30-688 Krakow, Poland.ORCID 0000-0002-3674-3581
Jagiellonian University · PLUniwersytet Komisji Edukacji Narodowej w Krakowie · PL

Funding

Uniwersytet Jagielloński Collegium Medicum N42/DBS/000027
6 · The paper itself

Abstract

Herein, 15 phenylpiperazine 3-benzyl-5,5-dimethylhydantoin derivatives (

Indexed as

Bacterial ProteinsHydantoinsMembrane Transport ProteinsStaphylococcus epidermidisCrystallography, X-Ray5,5-dimethylhydantoinBacterial ProteinsHydantoinsMembrane Transport ProteinsmsrA protein, Staphylococcus epidermidisefflux pumpefflux pump inhibitorsEPIsMsr(A)phenylpiperazine 5,5-dimethylhydantoinsStaphylococcus epidermidisX-ray crystallography

Identifiers

PMID32825366
PMCPMC7503621
OpenAlexW3070682734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.