Evidence map›Paper›PMID 32825311›Full record

ReviewBiomolecules2020

α-Lactalbumin, Amazing Calcium-Binding Protein.

Eugene A Permyakov

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07256769 (Synergic Role of Vitamin k, D-chiro Inositol and α-lactalbumin in Bone Homeostasis in Breast Cancer Patients Treated With Aromatase Inhibitors), which is not on this map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07256769 recruitingnot on this mapstarted 2025, after this paper: background citation

Synergic Role of Vitamin k, D-chiro Inositol and α-lactalbumin in Bone Homeostasis in Breast Cancer Patients Treated With Aromatase Inhibitors

TypeobservationalSponsorRegina Elena Cancer InstituteRan2025 to 2028Enrolled134ConditionsOsteoporosis Secondary, Breast Cancer FemalesArmsGroup 1: calcium carbonate/cholecalciferol, Group 2: Synostea® (calcium carbonate/cholecalciferol/vitamin K/α-lactalbumin/ d-chiro-inositol)
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 107 citations in OpenAlex.

  1. Review
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  10. Immune organoid for cancer immunotherapy.Acta pharmaceutica Sinica. B · 2025
    Review
  11. Article
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  13. Review
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  15. Article
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  17. Review
  18. Article
  19. Article
  20. Influence of divalent metal cations on α-lactalbumin fibril formation.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Eugene A PermyakovInstitute for Biological Instrumentation of the Russian Academy of Sciences, Federal Research Center Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russia.
Pushchino Scientific Center for Biological Research

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Lactalbumin (α-LA) is a small (Mr 14,200), acidic (pI 4-5), Ca

Indexed as

AnimalsAntineoplastic AgentsHumansHydrogen-Ion ConcentrationLactalbuminNeoplasmsOleic AcidAntineoplastic AgentsLactalbuminOleic Acidamyloid fibrilscytotoxicityfoldingliprotidesmetal bindingmolten globulenanoparticlesnanotubesstructureunfoldingα-lactalbumin

Identifiers

PMID32825311
PMCPMC7565966
OpenAlexW3060806001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.