Evidence map›Paper›PMID 32825198›Full record

ArticleMarine drugs2020

Sponge-Derived 24-Homoscalaranes as Potent Anti-Inflammatory Agents.

Bo-Rong Peng, Kuei-Hung Lai, Yu-Chia Chang, You-Ying Chen, Jui-Hsin Su, Yusheng M Huang, Po-Jen Chen, Steve Sheng-Fa Yu, Chang-Yih Duh, Ping-Jyun Sung

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Bo-Rong PengDoctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University, Kaohsiung 804201, Taiwan.
Kuei-Hung LaiGraduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0001-7220-6356
Yu-Chia ChangResearch Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333324, Taiwan.ORCID 0000-0002-7849-8254
You-Ying ChenNational Museum of Marine Biology and Aquarium, Pingtung 944401, Taiwan.
Jui-Hsin SuNational Museum of Marine Biology and Aquarium, Pingtung 944401, Taiwan.
Yusheng M HuangDepartment of Marine Recreation, National Penghu University of Science and Technology, Penghu 880011, Taiwan.
Po-Jen ChenDepartment of Cosmetic Science, Providence University, Taichung 433303, Taiwan.
Steve Sheng-Fa YuDoctoral Degree Program in Marine Biotechnology, Academia Sinica, Taipei 115201, Taiwan.
Chang-Yih DuhDoctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University, Kaohsiung 804201, Taiwan.
Ping-Jyun SungNational Museum of Marine Biology and Aquarium, Pingtung 944401, Taiwan.ORCID 0000-0002-6644-9236
National Sun Yat-sen University · TWChang Gung University of Science and Technology · TWInstitute of Chemistry, Academia Sinica · TWNational Dong Hwa University · TWNational Penghu University of Science and Technology · TWProvidence University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scalarane-type sesterterpenoids are known for their therapeutic potential in cancer treatments. However, the anti-inflammatory properties of this class of metabolites remain elusive. Our current work aimed to investigate the anti-inflammatory scalaranes from marine sponge

Indexed as

AnimalsAnti-Inflammatory AgentsHumansLeukocyte ElastaseMolecular StructureNeutrophilsPoriferaSecretory PathwaySesterterpenesStructure-Activity RelationshipSuperoxidesAnti-Inflammatory AgentsELANE protein, humanLeukocyte ElastaseSesterterpenesSuperoxides24-homoscalaraneanti-neutrophilic inflammationelastase releaselendenfeldaraneLendenfeldiaNADPH oxidasesesterterpenoidsuperoxide anion

Identifiers

PMID32825198
PMCPMC7551342
OpenAlexW3061719580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.