Evidence map›Paper›PMID 32825163›Full record

ReviewCells2020

The Diversity of Muscles and Their Regenerative Potential across Animals.

Letizia Zullo, Matteo Bozzo, Alon Daya, Alessio Di Clemente, Francesco Paolo Mancini, Aram Megighian, Nir Nesher, Eric Röttinger, Tal Shomrat, Stefano Tiozzo and 2 more

Abstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. All for One and One for All: Regenerating Skeletal Muscle.Cold Spring Harbor perspectives in biology · 2022
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Letizia ZulloIstituto Italiano di Tecnologia, Center for Micro-BioRobotics & Center for Synaptic Neuroscience and Technology (NSYN), 16132 Genova, Italy.
Matteo BozzoLaboratory of Developmental Neurobiology, Department of Earth, Environment and Life Sciences, University of Genova, Viale Benedetto XV 5, 16132 Genova, Italy.ORCID 0000-0002-7452-3758
Alon DayaFaculty of Marine Sciences, Ruppin Academic Center, Michmoret 40297, Israel.ORCID 0000-0002-0587-8782
Alessio Di ClementeIstituto Italiano di Tecnologia, Center for Micro-BioRobotics & Center for Synaptic Neuroscience and Technology (NSYN), 16132 Genova, Italy.
Francesco Paolo ManciniDepartment of Science and Technology, University of Sannio, 82100 Benevento, Italy.ORCID 0000-0002-9954-3608
Aram MegighianDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-7971-5310
Nir NesherFaculty of Marine Sciences, Ruppin Academic Center, Michmoret 40297, Israel.
Eric RöttingerInstitute for Research on Cancer and Aging (IRCAN), Université Côte d'Azur, CNRS, INSERM, 06107 Nice, France.
Tal ShomratFaculty of Marine Sciences, Ruppin Academic Center, Michmoret 40297, Israel.
Stefano TiozzoLaboratoire de Biologie du Développement de Villefranche-sur-Mer (LBDV), Sorbonne Université, CNRS, 06230 Paris, France.ORCID 0000-0003-2822-2783
Alberto ZulloDepartment of Science and Technology, University of Sannio, 82100 Benevento, Italy.
Simona CandianiLaboratory of Developmental Neurobiology, Department of Earth, Environment and Life Sciences, University of Genova, Viale Benedetto XV 5, 16132 Genova, Italy.ORCID 0000-0002-4453-5475

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells with contractile functions are present in almost all metazoans, and so are the related processes of muscle homeostasis and regeneration. Regeneration itself is a complex process unevenly spread across metazoans that ranges from full-body regeneration to partial reconstruction of damaged organs or body tissues, including muscles. The cellular and molecular mechanisms involved in regenerative processes can be homologous, co-opted, and/or evolved independently. By comparing the mechanisms of muscle homeostasis and regeneration throughout the diversity of animal body-plans and life cycles, it is possible to identify conserved and divergent cellular and molecular mechanisms underlying muscle plasticity. In this review we aim at providing an overview of muscle regeneration studies in metazoans, highlighting the major regenerative strategies and molecular pathways involved. By gathering these findings, we wish to advocate a comparative and evolutionary approach to prompt a wider use of "non-canonical" animal models for molecular and even pharmacological studies in the field of muscle regeneration.

Indexed as

AnimalsMusclesRegenerationdifferentiationevolutionmetazoansmuscle precursorsmyogenesisregenerative medicinetransdifferentiation

Identifiers

PMID32825163
PMCPMC7563492

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.