Evidence map›Paper›PMID 32825132›Full record

ArticleViruses2020

The Mottled Capsid of the

J Bernard Heymann, Bing Wang, William W Newcomb, Weimin Wu, Dennis C Winkler, Naiqian Cheng, Erin R Reilly, Ru-Ching Hsia, Julie A Thomas, Alasdair C Steven

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. The biology of jumbo phages.Nature communications · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

J Bernard HeymannLaboratory for Structural Biology Research, NIAMS, NIH, Bethesda, MD 20892, USA.ORCID 0000-0002-8872-5326
Bing WangLaboratory for Structural Biology Research, NIAMS, NIH, Bethesda, MD 20892, USA.
William W NewcombLaboratory for Structural Biology Research, NIAMS, NIH, Bethesda, MD 20892, USA.
Weimin WuLaboratory for Structural Biology Research, NIAMS, NIH, Bethesda, MD 20892, USA.
Dennis C WinklerLaboratory for Structural Biology Research, NIAMS, NIH, Bethesda, MD 20892, USA.ORCID 0000-0003-1445-6554
Naiqian ChengLaboratory for Structural Biology Research, NIAMS, NIH, Bethesda, MD 20892, USA.
Erin R ReillyThomas H. Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, NY 14623, USA.
Ru-Ching HsiaElectron Microscopy Core Imaging Facility, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.
Julie A ThomasThomas H. Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, NY 14623, USA.
Alasdair C StevenLaboratory for Structural Biology Research, NIAMS, NIH, Bethesda, MD 20892, USA.
Rochester Institute of Technology · USAdvanced Imaging Research (United States) · USUniversity of Maryland, Baltimore · US

Funding

Characterization of a giant virion and its unusual cargo of ejection proteinsUA5GM126533 · NIGMS · ROCHESTER INSTITUTE OF TECHNOLOGY · PI THOMAS, JULIE A. · 2018 to 2018
$427k
NIGMS NIH HHS UA5 GM126533NIGMS NIH HHS UA5GM126533
6 · The paper itself

Abstract

"Giant" phages have genomes of >200 kbp, confined in correspondingly large capsids whose assembly and maturation are still poorly understood. Nevertheless, the first assembly product is likely to be, as in other tailed phages, a procapsid that subsequently matures and packages the DNA. The associated transformations include the cleavage of many proteins by the phage-encoded protease, as well as the thinning and angularization of the capsid. We exploited an amber mutation in the viral protease gene of the

Indexed as

Virus AssemblyCapsidCapsid ProteinsCryoelectron MicroscopyDNA PackagingGenome, ViralGiant VirusesSalmonellaSalmonella PhagesVirionCapsid Proteins3D reconstructionbacteriophagecryoEM (cryo-electron microscopy)ejection proteinsscaffoldsingle particle analysisvirus

Identifiers

PMID32825132
PMCPMC7552025
OpenAlexW3074886798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.