Evidence map›Paper›PMID 32825046›Full record

ArticleInternational journal of molecular sciences2020

Carbon Fibers as a New Type of Scaffold for Midbrain Organoid Development.

Anna Tejchman, Agnieszka Znój, Paula Chlebanowska, Aneta Frączek-Szczypta, Marcin Majka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  9. Organoid scaffold materials: research and application.Frontiers in bioengineering and biotechnology · 2025
    Review
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  16. Bioengineering Approaches for the Advanced Organoid Research.Advanced materials (Deerfield Beach, Fla.) · 2021
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anna TejchmanDepartment of Transplantation, Faculty of Medicine, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265, 30-663 Kraków, Poland.ORCID 0000-0002-9985-7228
Agnieszka ZnójDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, Poland.
Paula ChlebanowskaDepartment of Transplantation, Faculty of Medicine, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265, 30-663 Kraków, Poland.
Aneta Frączek-SzczyptaDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, Poland.
Marcin MajkaDepartment of Transplantation, Faculty of Medicine, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265, 30-663 Kraków, Poland.ORCID 0000-0002-0429-681X
Jagiellonian University · PLAGH University of Krakow · PL

Funding

Narodowe Centrum Nauki 2015/17/B/NZ5/00294Wydział Lekarski, Uniwersytet Jagielloński Collegium Medicum K/ZDS/007055
6 · The paper itself

Abstract

The combination of induced pluripotent stem cell (iPSC) technology and 3D cell culture creates a unique possibility for the generation of organoids that mimic human organs in in vitro cultures. The use of iPS cells in organoid cultures enables the differentiation of cells into dopaminergic neurons, also found in the human midbrain. However, long-lasting organoid cultures often cause necrosis within organoids. In this work, we present carbon fibers (CFs) for medical use as a new type of scaffold for organoid culture, comparing them to a previously tested copolymer poly-(lactic-

Indexed as

Acrylic ResinsCarbon FiberCell DifferentiationCells, CulturedDopaminergic NeuronsHomeodomain ProteinsHumansInduced Pluripotent Stem CellsMesencephalonOrganoidsPolylactic Acid-Polyglycolic Acid CopolymerTissue EngineeringTissue ScaffoldsTranscription FactorsTyrosine 3-MonooxygenaseAcrylic ResinsCarbon Fiberhomeobox protein PITX3Homeodomain ProteinspolyacrylonitrilePolylactic Acid-Polyglycolic Acid CopolymerTranscription FactorsTyrosine 3-Monooxygenase3D modelcarbon fibersLMX1ANURR1organoidParkinson’s diseasePITX3scaffoldTH

Identifiers

PMID32825046
PMCPMC7504539
OpenAlexW3062797765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.