Evidence map›Paper›PMID 32824922›Full record

ArticleGenes2020

Leonardo P Stuchi, Márcia Maria U Castanhole-Nunes, Nathália Maniezzo-Stuchi, Patrícia M Biselli-Chicote, Tiago Henrique, João Armando Padovani Neto, Dalisio de-Santi Neto, Ana Paula Girol, Erika C Pavarino, Eny Maria Goloni-Bertollo

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Frontiers in oncology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma.European journal of histochemistry : EJH · 2023
    Article
  8. Regulation ofInternational journal of molecular sciences · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The Keap1/Nrf2 Signaling Pathway in the Thyroid-2020 Update.Antioxidants (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Leonardo P StuchiResearch Unit in Genetics and Molecular Biology-UPGEM, Faculty of Medicine of São José do Rio Preto-FAMERP, São José do Rio Preto 15090-000, Brazil.ORCID 0000-0002-9176-7818
Márcia Maria U Castanhole-NunesResearch Unit in Genetics and Molecular Biology-UPGEM, Faculty of Medicine of São José do Rio Preto-FAMERP, São José do Rio Preto 15090-000, Brazil.ORCID 0000-0002-5506-8155
Nathália Maniezzo-StuchiPadre Albino University Center-UNIFIPA, Catanduva, São Paulo 15809-144, Brazil.ORCID 0000-0002-3428-0958
Patrícia M Biselli-ChicoteResearch Unit in Genetics and Molecular Biology-UPGEM, Faculty of Medicine of São José do Rio Preto-FAMERP, São José do Rio Preto 15090-000, Brazil.
Tiago HenriqueLaboratory of Molecular Markers and Bioinformatics, Department of Molecular Biology, Faculty of Medicine of São José do Rio Preto -FAMERP, São José do Rio Preto 15090-000, Brazil.
João Armando Padovani NetoDepartment of Otolaryngology and Head and Neck Surgery, Faculty of Medicine of São José do Rio Preto -FAMERP, São José do Rio Preto 15090-000, Brazil.
Dalisio de-Santi NetoPathological Anatomy Service, Hospital de Base, Foundation Regional Faculty of Medicine of São José do Rio Preto-FUNFARME, São José do Rio Preto 15090-000, Brazil.
Ana Paula GirolPadre Albino University Center-UNIFIPA, Catanduva, São Paulo 15809-144, Brazil.ORCID 0000-0002-8760-8945
Erika C PavarinoResearch Unit in Genetics and Molecular Biology-UPGEM, Faculty of Medicine of São José do Rio Preto-FAMERP, São José do Rio Preto 15090-000, Brazil.
Eny Maria Goloni-BertolloResearch Unit in Genetics and Molecular Biology-UPGEM, Faculty of Medicine of São José do Rio Preto-FAMERP, São José do Rio Preto 15090-000, Brazil.ORCID 0000-0002-2622-4673
Faculdade de Medicina de São José do Rio Preto · BRFundação Padre Albino · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deregulation of VEGFA (Vascular Endothelial Growth Factor A) and NFE2L2 (Nuclear Factor (Erythroid-derived 2)-Like 2), involved in angiogenesis and oxidative stress, can lead to thyroid cancer progression. MiR-17-5p and miR-612 are possible regulators of these genes and may promote thyroid disorders. In order to evaluate the involvement of VEGFA, NFE2L2, hsa-miR-17-5p, and hsa-miR-612 in thyroid pathology, we examined tissue samples from colloid goiter, papillary thyroid cancer (PTC), and a normal thyroid. We found higher levels of VEGFA and NFE2L2 transcripts and the VEGFA protein in goiter and PTC samples than in normal tissue. In the goiter, miR-612 and miR-17-5p levels were lower than those in PTC. Tumors, despite showing lower

Indexed as

ApoptosisBiomarkers, TumorCase-Control StudiesCell ProliferationFemaleGene Expression Regulation, NeoplasticGoiter, NodularHumansMaleMicroRNAsMiddle AgedNF-E2-Related Factor 2PrognosisThyroid Cancer, PapillaryThyroid NeoplasmsTumor Cells, CulturedBiomarkers, TumorMicroRNAsMIRN17 microRNA, humanMIRN612 microRNA, humanNFE2L2 protein, humanNF-E2-Related Factor 2Vascular Endothelial Growth Factor AVEGFA protein, humangoitermicroRNAsNF-E2-related factor 2thyroid neoplasmsvascular endothelial growth factor A

Identifiers

PMID32824922
PMCPMC7563674
OpenAlexW3059402998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.