Evidence map›Paper›PMID 32824891›Full record

ReviewPharmaceuticals (Basel, Switzerland)2020

In Vitro Modeling of Bradykinin-Mediated Angioedema States.

François Marceau, Hélène Bachelard, Xavier Charest-Morin, Jacques Hébert, Georges E Rivard

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

François MarceauCentre de Recherche du CHU de Québec-Université Laval, Québec, QC G1V 4G2, Canada.
Hélène BachelardCentre de Recherche du CHU de Québec-Université Laval, Québec, QC G1V 4G2, Canada.ORCID 0000-0001-7320-3704
Xavier Charest-MorinCentre de Recherche du CHU de Québec-Université Laval, Québec, QC G1V 4G2, Canada.
Jacques HébertService D'allergie, CHU de Québec-Université Laval, Québec, QC G1V 4G2, Canada.
Georges E RivardCHU Sainte-Justine, Université de Montréal, Montréal, QC H3T 1C5, Canada.ORCID 0000-0002-2861-9441
Université Laval · CACentre Hospitalier Universitaire Sainte-Justine · CA

Funding

Angio-Oedème Héréditaire du Québec 2019-20CIHR MOP-93773Fonds de recherche santé du Québec Studentship AwardShire IIR-CAN-000902, IIR-CAN-001615
6 · The paper itself

Abstract

Kinins (peptides related to bradykinin, BK) are formed from circulating substrates, the kininogens, by the action of two proteases, the kallikreins. The only clinical application of a BK receptor ligand, the B

Indexed as

acquired angioedemaanalytical techniques for kininsbradykininhereditary angioedemakallikrein–kinin system

Identifiers

PMID32824891
PMCPMC7559923
OpenAlexW3057476791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.