Evidence map›Paper›PMID 32824852›Full record

ArticleGenes2020

Basal Levels of CD18 Antigen Presenting Cells in Cow Milk Associate with Copy Number Variation of Fc Gamma Receptors.

Eyal Seroussi, Shlomo E Blum, Oleg Krifucks, Andrey Shirak, Shamay Jacoby, Gabriel Leitner

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eyal SeroussiInstitute of Animal Science, ARO, Volcani Center, HaMaccabim Road, P.O. Box 15159, Rishon LeTsiyon 7528809, Israel.ORCID 0000-0001-6191-8948
Shlomo E BlumNational Mastitis Reference Center, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.ORCID 0000-0002-5451-9997
Oleg KrifucksNational Mastitis Reference Center, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.
Andrey ShirakInstitute of Animal Science, ARO, Volcani Center, HaMaccabim Road, P.O. Box 15159, Rishon LeTsiyon 7528809, Israel.
Shamay JacobyInstitute of Animal Science, ARO, Volcani Center, HaMaccabim Road, P.O. Box 15159, Rishon LeTsiyon 7528809, Israel.
Gabriel LeitnerNational Mastitis Reference Center, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.
Agricultural Research Organization · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differentiation of cells by flow cytometry provides informative somatic cell counts (SCCs) that allow analyzing leukocyte population patterns in udder infections of different etiologies. Postulating that this approach also enhances the statistical power to detect genetic variants linked to cell levels in milk of healthy mammary glands, we used monoclonal antibodies anti-CD18, anti-CD4, anti--CD14, and anti-PMN to count cells presenting these surface antigens, and performed a genome-wide association study of these counts in 125 Israeli Holsteins genotyped using SNP BeadChips. We identified an informative haplotype of 15 SNPs in the centromeric end of BTA3 that was strongly associated with CD18 cells (

Indexed as

Gene DosageAllelesAnimalsAntigen-Presenting CellsBiomarkersCattleCD18 AntigensCloning, MolecularDNA Copy Number VariationsFemaleGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksGenome-Wide Association StudyHaplotypesLeukocyte CountBiomarkersCD18 AntigensReceptors, IgGclassification determinantcluster of differentiationGWASimmunogeneticsmastitismilkSNP BeadChip

Identifiers

PMID32824852
PMCPMC7464846
OpenAlexW3052334636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.