ArticleJournal of clinical medicine2020
A Novel Technique of Endoscopic Papillectomy with Hybrid Endoscopic Submucosal Dissection for Ampullary Tumors: A Proof-of-Concept Study (with Video).
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- Comparative efficacy and safety of hybrid versus conventional endoscopic submucosal dissection for non-ampullary duodenal submucosal tumors.Surgical endoscopy · 2026Article
- Endoscopic ultrasound-assisted rendezvous technique followed by dual-duct drainage using a double-lumen papillotome: a salvage strategy for postendoscopic papillectomy stricture.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- New Endoscopic Strategy for Ampullary Tumor and Superficial Nonampullary Duodenal Epithelial Tumor Extending Into Papillary Area.Journal of hepato-biliary-pancreatic sciences · 2025Observational
- Efficacy and safety of endoscopic submucosal dissection versus endoscopic papillectomy for managing laterally spreading duodenal papillary tumors.Clinical endoscopy · 2025Article
- Two-stage cap-assisted endoscopic mucosal resection and papillectomy for duodenal papillary tumors with lateral growth.Endoscopy · 2024Article
- Peroral cholecystoscopy-guided interventions through a lumen-apposing metal stent after EUS-guided gallbladder drainage: proof-of-concept study in a swine model.iGIE : innovation, investigation and insights · 2024Article
- Current status of and future issues related to endoscopic papillectomy.Nagoya journal of medical science · 2023Review
- Updates on the Management of Ampullary Neoplastic Lesions.Diagnostics (Basel, Switzerland) · 2023Review
- Recent Advances in Pancreato-Biliary Endoscopic Intervention: How to Resolve Unmet Needs in Pancreato-Biliary Diseases Endoscopically.Journal of clinical medicine · 2022Article
- Investigation of the Indications for Endoscopic Papillectomy and Transduodenal Ampullectomy for Ampullary Tumors.Journal of clinical medicine · 2021Article
- Endoscopic Papillectomy for Adenocarcinoma at the Duodenal Papilla - Will It Still Open a Pandora's Box?Internal medicine (Tokyo, Japan) · 2021Article
Corrections and comments
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Authors and funding
17 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic papillectomy (EP) carries a potential risk of procedure-related adverse events and incomplete resection. Since hybrid endoscopic submucosal dissection (ESD) had been established as an alternative option for relatively large and difficult gastrointestinal tumors, we evaluated a novel EP with hybrid ESD (hybrid ESD-EP) for curative safe margin in this proof-of-concept study.
methodsA total of eight cases who underwent hybrid ESD-EP between 2018 and 2020 were identified from our prospectively maintained database. Hybrid ESD-EP involved a (sub)circumferential incision with partial submucosal dissection, and subsequent snare resection of ampullary tumors, which was performed by two endoscopists with expertise in ESD or endoscopic retrograde cholangiopancreatography. Demographic data and clinicopathological outcomes were retrospectively evaluated.
resultsEn bloc resection was achieved by hybrid ESD-EP in all eight cases, with the median procedure time of 112 (range: 65-170) minutes. The median diameters of the resected specimens and tumors were 18 and 12 mm, respectively. All lateral margins were clear, whereas vertical margin was uncertain in three (38%), resulting in the complete resection rate of 63%. Postoperative bleeding and pancreatitis developed in each one (13%). No tumor recurrence was observed even in those cases with uncertain vertical margin, after a median follow-up of 244 (range, 97-678) days.
conclusionsHybrid ESD-EP seems to be feasible and promising in ensuring the lateral resection margin. However, further investigations, especially to secure the vertical margin and to shorten the procedure time, should be required.
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