ReviewToxics2020
Human Biomonitoring of Glyphosate Exposures: State-of-the-Art and Future Research Challenges.
Review in Toxics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Urinary Glyphosate Concentrations among Pregnant Participants in a Randomized, Crossover Trial of Organic and Conventional Diets.Environmental health perspectives · 2023Trial
- A robust dilute-and-inject ion chromatography - Tandem mass spectrometry for urinary glyphosate quantification.MethodsX · 2026Article
- Vitamin E Attenuates Glyphosate-Induced Multi-Organ Toxicity and Redox Imbalance in Rats: Biochemical and Histopathological Evidence.Veterinary sciences · 2026Article
- Presence of glyphosate in endometrial cancer tissue: A cross-sectional study.Toxicology reports · 2026Article
- Exposure of Farmers and Spouses to Glyphosate in Morocco: Urinary Levels and Predictors of Exposure.Toxics · 2026Article
- Network-based integrative analysis of multi-level regulatory mechanisms associated with glyphosate exposure.Frontiers in bioinformatics · 2026Article
- Review
- Scientific and Regulatory Perspectives on Chemical Risk Assessment of Pesticides in the European Union.Journal of xenobiotics · 2025Review
- Multi-Omics Alterations in Rat Kidneys upon Chronic Glyphosate Exposure.Biomolecules · 2025Article
- Characterization of pesticide exposures and their associations with asthma morbidity in a predominantly low-income urban pediatric cohort in Baltimore City.Environmental research · 2024Article
- Sociodemographic and dietary determinants of glyphosate exposure in a NYC-based pregnancy cohort.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Article
- Ameliorative effect of licorice extract against the detrimental effect of glyphosate-based pesticide: Toxicity and health.Heliyon · 2024Article
- Urinary biomonitoring of glyphosate exposure among male farmers and nonfarmers in the Biomarkers of Exposure and Effect in Agriculture (BEEA) study.Environment international · 2024Article
- Glyphosate-based herbicide metabolic profiles in human urine samples through proton nuclear magnetic resonance analysis.ADMET & DMPK · 2024Article
- Glyphosate and a glyphosate-based herbicide dysregulate the epigenetic landscape of Homeobox A10 (Frontiers in toxicology · 2024Article
- Overview of human health effects related to glyphosate exposure.Frontiers in toxicology · 2024Review
- Determination of pesticide residues in urine by chromatography-mass spectrometry: methods and applications.Frontiers in public health · 2024Review
- Estimation of Glyphosate biological half-life among farmers and residents in Thailand.Human and ecological risk assessment : HERA · 2024Article
- The Effect of Pesticide Spray Season and Residential Proximity to Agriculture on Glyphosate Exposure among Pregnant People in Southern Idaho, 2021.Environmental health perspectives · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Glyphosate continues to attract controversial debate following the International Agency for Research on Cancer carcinogenicity classification in 2015. Despite its ubiquitous presence in our environment, there remains a dearth of data on human exposure to both glyphosate and its main biodegradation product aminomethylphosphonic (AMPA). Herein, we reviewed and compared results from 21 studies that use human biomonitoring (HBM) to measure urinary glyphosate and AMPA. Elucidation of the level and range of exposure was complicated by differences in sampling strategy, analytical methods, and data presentation. Exposure data is required to enable a more robust regulatory risk assessment, and these studies included higher occupational exposures, environmental exposures, and vulnerable groups such as children. There was also considerable uncertainty regarding the absorption and excretion pattern of glyphosate and AMPA in humans. This information is required to back-calculate exposure doses from urinary levels and thus, compared with health-based guidance values. Back-calculations based on animal-derived excretion rates suggested that there were no health concerns in relation to glyphosate exposure (when compared with EFSA acceptable daily intake (ADI)). However, recent human metabolism data has reported as low as a 1% urinary excretion rate of glyphosate. Human exposures extrapolated from urinary glyphosate concentrations found that upper-bound levels may be much closer to the ADI than previously reported.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.