ReviewPolymers2020
State of the Art on Biomaterials for Soft Tissue Augmentation in the Oral Cavity. Part I: Natural Polymers-Based Biomaterials.
Review in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Collagen Matrix Versus Subepithelial Connective Tissue for Recession Coverage: A Systematic Review.Oral diseases · 2025Pooled it
- Autogenous graft versus collagen matrices for peri-implant soft tissue augmentation. A systematic review and network meta-analysis.Clinical oral investigations · 2024Pooled it
- Review
- Enhancing Healing in Oral Surgical Procedures: A Review on Biomaterials, Growth Factors, and Tissue Engineering.Cureus · 2026Review
- Mechanical and Biological Properties of Nondecellularized Human Wharton's Jelly Matrix for Soft Tissue Graft Material: An In Vitro Study.European journal of dentistry · 2026Article
- A standardized rat model of maxillary anterior periodontal soft tissue defect for the evaluation of soft tissue graft materials.Frontiers in bioengineering and biotechnology · 2026Article
- The Role and Involvement of Functional Three-Dimensional Porcine-Derived Collagen Matrix Biomaterials in Periodontal Regeneration: A Comprehensive Review.Journal of functional biomaterials · 2025Review
- Apical Positioned Flap with a Combination of Mucograft and Fibro-Gide for Augmenting Keratinized Gingiva with Thin Gingival Phenotype: A Case Report.European journal of dentistry · 2025Article
- Analysis of the Expression and Activity of Cyclooxygenases COX-1 and COX-2 in THP-1 Monocytes and Macrophages Cultured with Xenogenic Collagen Matrices Biofunctionalized with the Injectable Platelet-Rich Fibrin.International journal of molecular sciences · 2025Article
- A Novel Pre-Customized Saddle-Shape Soft Tissue Substitute for Volume Augmentation: An Ex Vivo Study in Pig Mandibles.Materials (Basel, Switzerland) · 2025Article
- Polymer-Based Scaffolds as an Implantable Material in Regenerative Dentistry: A Review.Journal of functional biomaterials · 2025Review
- The Effect of Carbodiimide Crosslinkers on Gelatin Hydrogel as a Potential Biomaterial for Gingival Tissue Regeneration.Gels (Basel, Switzerland) · 2024Article
- Perfusable Tissue Bioprinted into a 3D-Printed Tailored Bioreactor System.Bioengineering (Basel, Switzerland) · 2024Article
- Electrophoretically Co-Deposited Collagen-Lactoferrin Membranes with Enhanced Pro-Regenerative Properties for Oral Soft Tissue Regeneration.International journal of molecular sciences · 2023Article
- Hydrogel-Based Biomaterial as a Scaffold for Gingival Regeneration: A Systematic Review of In Vitro Studies.Polymers · 2023Review
- Tissue integration and biodegradation of soft tissue substitutes with and without compression: an experimental study in the rat.Clinical oral investigations · 2023Article
- Graft Polymerization of Acrylamide in an Aqueous Dispersion of Collagen in the Presence of Tributylborane.Polymers · 2022Article
- Characterizing cell recruitment into isotropic and anisotropic biomaterials by quantification of spatial density gradientsFrontiers in bioengineering and biotechnology · 2022Article
- Design of customized soft-tissue substitutes for posterior single-tooth defects: A proof-of-concept in-vitro study.Clinical oral implants research · 2021Article
- Natural Polymers for the Maintenance of Oral Health: Review of Recent Advances and Perspectives.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Oral soft tissue thickening or grafting procedures are often necessary to cover tooth recession, re-establish an adequate width of keratinized tissue, correct mucogingival deformities improving esthetics, prepare a site for an implant or prosthetics, for ridge preservation procedures, and soft tissue contouring around dental implants. Gingival recession and root or implant exposure are commonly associated and have led to mucogingival deficiencies that have traditionally been treated with free gingival grafts and autogenous soft tissue grafts. The latter represents the gold standard in acquiring a functionally adequate zone of keratinized attached gingiva. However, soft tissue substitutes are more usually employed because they lessen morbidity and abbreviate surgical time. This review is aimed at assessing oral soft tissue augmentation techniques and biomaterials used from existing literature, principally concerning scaffolds from both human and animal-based tissue derivatives matrices. In order to avoid the use of human donor tissue, the xenogenic collagen matrices are proposed for soft tissue augmentation. In general, all of them have provided the remodeling processes and enhanced the formation of new connective tissue within the matrix body.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.