Evidence map›Paper›PMID 32824696›Full record

ArticleBiomolecules2020

Benedito M Dos Santos, Daniel T G Gonzaga, Fernando C da Silva, Vitor F Ferreira, Celia R S Garcia

Open access · goldAbstract readComparative Study
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Changes in KInternational journal of molecular sciences · 2023
    Review
  7. Article
  8. Evidence of G-Protein-Coupled Receptors (GPCR) in the Parasitic ProtozoaInternational journal of molecular sciences · 2021
    Review
  9. Antiplasmodial activity of the natural product compounds alstonine and himbeline.International journal for parasitology. Drugs and drug resistance · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Benedito M Dos SantosDepartment of Clinical and Toxicological Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo-SP 05508-000, Brazil.ORCID 0000-0002-2196-260X
Daniel T G GonzagaFundação Centro Universitário Estadual da Zona Oeste, Unidade de Farmácia, Rio de Janeiro-RJ 23070-200, Brazil.
Fernando C da SilvaDepartment of Organic Chemistry, Institute of Chemistry, Universidade Federal Fluminense, Niterói-RJ 24220-900, Brazil.
Vitor F FerreiraDepartment of Pharmaceutical Technology, Pharmacy School, Universidade Federal Fluminense, Niterói-RJ 24220-900, Brazil.ORCID 0000-0002-2166-766X
Celia R S GarciaDepartment of Clinical and Toxicological Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo-SP 05508-000, Brazil.
Universidade de São Paulo · BRUniversidade Federal Fluminense · BRUniversidade Estadual da Zona Oeste · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 145654/2019-2Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/010.101106/2018Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/203.191/2017Fundação de Amparo à Pesquisa do Estado de São Paulo 17/08684-7
6 · The paper itself

Abstract

The search for new compounds with antimalarial activity is urgent, as resistance to ones in the classical drug, has already been described in more than one continent. Compounds derived from 1,2,3-triazoles are effective against parasites and bacteria. Here, we evaluated the potential antimalarial activity against the human malaria parasite

Indexed as

AntimalarialsCell ProliferationGene Knockout TechniquesHEK293 CellsHumansInhibitory Concentration 50Molecular StructurePlasmodium falciparumProtozoan ProteinsReceptors, G-Protein-CoupledTriazolesAntimalarialsProtozoan ProteinsReceptors, G-Protein-CoupledTriazolesantimalarialG-protein coupled receptorheterocyclesPfSR25Plasmodium falciparumscreening

Identifiers

PMID32824696
PMCPMC7465636
OpenAlexW3058847565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.