Evidence map›Paper›PMID 32824645›Full record

ArticleAntibodies (Basel, Switzerland)2020

Severe Intraoperative Anaphylaxis Related to Thymoglobulin during Living Donor Kidney Transplantation.

Muhammad I Saeed, Ryan D Nicklas, Vikas Kumar, Rajan Kapoor, Imran Y Gani

Open access · goldAbstract readCase Reports
In one paragraph

Article in Antibodies (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A case report: anaphylaxis to cefazolin during renal transplant surgery.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Muhammad I SaeedDepartment of Surgery, Augusta University Medical Center, Augusta, GA 30912, USA.ORCID 0000-0002-0627-1253
Ryan D NicklasDepartment of Anesthesiology, Augusta University Medical Center, Augusta, GA 30912, USA.
Vikas KumarDepartment of Anesthesiology, Augusta University Medical Center, Augusta, GA 30912, USA.
Rajan KapoorDepartment of Nephrology, Hypertension and Transplant Medicine, Augusta University Medical Center, Augusta, GA 30912, USA.
Imran Y GaniDepartment of Nephrology, Hypertension and Transplant Medicine, Augusta University Medical Center, Augusta, GA 30912, USA.ORCID 0000-0002-4813-5022
Augusta University Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaphylaxis secondary to thymoglobulin (anti-thymocyte globulin) is a rare condition that can be life threatening. Thymoglobulin is a rabbit-derived T-cell depleting polyclonal immunoglobulin. It is commonly used for induction immunosuppression and/or for treatment of acute rejection in renal transplantation. We report a case of a living kidney transplant recipient who developed intraoperative anaphylactic shock secondary to thymoglobulin. The patient had a history of pet rabbit exposure. This case report highlights the importance of prompt identification and management of intraoperative anaphylaxis, which is key to a successful outcome. Induction immunosuppression selection based on patient characteristics is important. Communication between the anesthesia team and surgeons played a key role in stopping the donor surgery.

Indexed as

anaphylactic shockliving donor kidney transplantationrabbit anti-thymocyte globulin

Identifiers

PMID32824645
PMCPMC7551055
OpenAlexW3049408501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.