ArticleAntioxidants (Basel, Switzerland)2020
S-Thiolation Targets Albumin in Heart Failure.
Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- A Pichia pastoris-based platform for large-scale production of functional recombinant human serum albumin with therapeutic efficacy.Bioprocess and biosystems engineering · 2026Article
- High CALLY index is independently associated with lower odds of preserved ratio impaired spirometry (PRISm) and provides incremental predictive value: a retrospective observational study.Frontiers in medicine · 2026Article
- Albumin: a novel biomarker for predicting intraoperative hypothermia in HSCR.Annals of medicine · 2025Article
- Safety of human serum albumin infusion in heart failure patients with hypoproteinemia: a propensity score-matched analysis.Clinics (Sao Paulo, Brazil) · 2025Article
- N-Acetylcysteine, N-Acetylcysteine Amide, and Thioredoxin Mimetic Peptides Regenerate Mercaptoalbumin and Exhibit Antioxidant Activity.Antioxidants (Basel, Switzerland) · 2024Article
- Albumin, an interesting and functionally diverse protein, varies from 'native' to 'effective' (Review).Molecular medicine reports · 2024Review
- Albumin Thiolation and Oxidative Stress Status in Patients with Aortic Valve Stenosis.Biomolecules · 2023Article
- Development and validation of a nomogram to predict mortality risk in patients with ischemic heart disease.Frontiers in cardiovascular medicine · 2023Article
- Serum albumin and the short-term mortality in individuals with congestive heart failure in intensive care unit: an analysis of MIMIC.Scientific reports · 2022Article
- N-Acetylcysteine Regenerates In Vivo Mercaptoalbumin.Antioxidants (Basel, Switzerland) · 2022Article
- The Burden of Impaired Serum Albumin Antioxidant Properties and Glyco-Oxidation in Coronary Heart Disease Patients with and without Type 2 Diabetes Mellitus.Antioxidants (Basel, Switzerland) · 2022Article
- Mercaptoalbumin Is Associated with Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting.Antioxidants (Basel, Switzerland) · 2022Article
- Article
- Clinical Significance of Serum Albumin and Implications of FcRn Inhibitor Treatment in IgG-Mediated Autoimmune Disorders.Frontiers in immunology · 2022Review
- Serum Albumin: A Multifaced Enzyme.International journal of molecular sciences · 2021Review
- Lipid peroxidation derived reactive carbonyl species in free and conjugated forms as an index of lipid peroxidation: limits and perspectives.Redox biology · 2021Article
- Serum Albumin Redox States: More Than Oxidative Stress Biomarker.Antioxidants (Basel, Switzerland) · 2021Review
- Oxidized Albumin as a Mediator of Kidney Disease.Antioxidants (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Human serum albumin (HSA) is associated with several physiological functions, such as maintaining oncotic pressure and microvascular integrity, among others. It also represents the major and predominant antioxidant in plasma due to the presence of the Cys34 sulfhydryl group. In this study, we assessed qualitative and quantitative changes in HSA in patients with heart failure (HF) and their relationship with the severity of the disease. We detected by means of mass spectrometry a global decrease of the HSA content in the plasma of HF patients in respect to control subjects, a significant increase of thio-HSA with a concomitant decrease in the reduced form of albumin. Cysteine and, at a lesser extent, homocysteine represent the most abundant thiol bound to HSA. A strong inverse correlation was also observed between cysteine-HSA and peak VO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.