Evidence map›Paper›PMID 32824464›Full record

ArticleJournal of fungi (Basel, Switzerland)2020

Relative Frequency of Paradoxical Growth and Trailing Effect with Caspofungin, Micafungin, Anidulafungin, and the Novel Echinocandin Rezafungin against

Zoltán Tóth, Lajos Forgács, Tamás Kardos, Renátó Kovács, Jeffrey B Locke, Gábor Kardos, Fruzsina Nagy, Andrew M Borman, Awid Adnan, László Majoros

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Caspofungin paradoxical growth inFrontiers in cellular and infection microbiology · 2025
    Article
  3. Exploring the Potential of Extracts fromPharmaceuticals (Basel, Switzerland) · 2023
    Article
  4. Microorganisms · 2022
    Article
  5. Article
  6. Recent Antifungal Pipeline Developments againstJournal of fungi (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Zoltán TóthDepartment of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Lajos ForgácsDepartment of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Tamás KardosDepartment of Pulmonology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Renátó KovácsDepartment of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0003-3946-2424
Jeffrey B LockeCidara Therapeutics, Inc., 6310 Nancy Ridge Dr., Suite 101, San Diego, CA 92121, USA.
Gábor KardosDepartment of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Fruzsina NagyDepartment of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Andrew M BormanUK National Mycology Reference Laboratory, Public Health England, Science Quarter, Southmead Hospital, Bristol BS10 5NB, UK.ORCID 0000-0003-0585-5721
Awid AdnanDepartment of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
László MajorosDepartment of Medical Microbiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
University of Debrecen · HUCidara Therapeutics (United States) · USUniversity of Exeter · GB

Funding

Medical Research Council MR/N006364/2Ministry for Innovation and Technology EFOP-3.6.3-VEKOP-16-2017-00009Ministry for Innovation and Technology ÚNKP-19-3
6 · The paper itself

Abstract

Rezafungin is a next-generation echinocandin that has favorable pharmacokinetic properties. We compared the occurrence of paradoxical growth (PG) and trailing effect (TE) characteristics to echinocadins with rezafungin, caspofungin, micafungin and anidulafungin using 365 clinical

Indexed as

CandidaC. aurisechinocandinparadoxical growthrezafungintrailing effect

Identifiers

PMID32824464
PMCPMC7560028
OpenAlexW3049451044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.