Evidence map›Paper›PMID 32824297›Full record

ArticleInternational journal of molecular sciences2020

The New Model of Snail Expression Regulation: The Role of MRTFs in Fast and Slow Endothelial-Mesenchymal Transition.

Katarzyna Sobierajska, Wojciech M Ciszewski, Ewa Macierzynska-Piotrowska, Wanda Klopocka, Patrycja Przygodzka, Magdalena Karakula, Karolina Pestka, Marta E Wawro, Jolanta Niewiarowska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  8. TheEvidence-based complementary and alternative medicine : eCAM · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Katarzyna SobierajskaDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0003-3510-0098
Wojciech M CiszewskiDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0001-6251-6043
Ewa Macierzynska-PiotrowskaDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 92-215 Lodz, Poland.
Wanda KlopockaDepartment of Biochemistry and Cell Biology, Cardinal Stefan Wyszynski University in Warsaw, 01-938 Warsaw, Poland.
Patrycja PrzygodzkaInstitute of Medical Biology, PAS, 93-232 Lodz, Poland.ORCID 0000-0001-7529-8815
Magdalena KarakulaDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 92-215 Lodz, Poland.
Karolina PestkaDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 92-215 Lodz, Poland.
Marta E WawroDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 92-215 Lodz, Poland.
Jolanta NiewiarowskaDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0003-0561-7766
Medical University of Lodz · PLCardinal Stefan Wyszynski University in Warsaw · PLInstitute for Medical Biology · PL

Funding

Narodowe Centrum Badań i Rozwoju MOMENTO Pol-Nor/209521/5/2013
6 · The paper itself

Abstract

Endothelial-mesenchymal transition (EndMT) is a crucial phenomenon in regulating the development of diseases, including cancer metastasis and fibrotic disorders. The primary regulators of disease development are zinc-finger transcription factors belonging to the Snail family. In this study, we characterized the myocardin-related transcription factor (MRTF)-dependent mechanisms of a human

Indexed as

Epithelial-Mesenchymal TransitionCell LineEndothelial CellsHumansPromoter Regions, GeneticProtein BindingSnail Family Transcription FactorsTranscriptional ActivationTranscription FactorsMRTFB protein, humanSNAI1 protein, humanSnail Family Transcription FactorsTranscription FactorsEndMTMRTFsSnail

Identifiers

PMID32824297
PMCPMC7461591
OpenAlexW3049627893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.