Evidence map›Paper›PMID 32824259›Full record

ArticleSensors (Basel, Switzerland)2020

Real-Time Wireless Platform for In Vivo Monitoring of Bone Regeneration.

Pablo Blázquez-Carmona, Manuel Sanchez-Raya, Juan Mora-Macías, Juan Antonio Gómez-Galán, Jaime Domínguez, Esther Reina-Romo

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Bone regeneration during osteoporosis: a translationalFrontiers in bioengineering and biotechnology · 2025
    Article
  5. Article
  6. Article
  7. Sensor Technology in Fracture Healing.Indian journal of orthopaedics · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pablo Blázquez-CarmonaEscuela Técnica Superior de Ingeniería, Universidad de Sevilla, 41092 Seville, Spain.ORCID 0000-0002-7605-5812
Manuel Sanchez-RayaEscuela Técnica Superior de Ingeniería, Universidad de Huelva, 21007 Huelva, Spain.ORCID 0000-0001-6883-4317
Juan Mora-MacíasEscuela Técnica Superior de Ingeniería, Universidad de Huelva, 21007 Huelva, Spain.ORCID 0000-0002-7997-9789
Juan Antonio Gómez-GalánEscuela Técnica Superior de Ingeniería, Universidad de Huelva, 21007 Huelva, Spain.ORCID 0000-0003-1304-8372
Jaime DomínguezEscuela Técnica Superior de Ingeniería, Universidad de Sevilla, 41092 Seville, Spain.ORCID 0000-0002-0491-7911
Esther Reina-RomoEscuela Técnica Superior de Ingeniería, Universidad de Sevilla, 41092 Seville, Spain.ORCID 0000-0002-5714-465X
Universidad de Huelva · ESUniversidad de Sevilla · ES

Funding

Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía US-1261691Ministerio de Ciencia, Innovación y Universidades FPU17/05361Ministerio de Economía y Competitividad DPI2017-82501-P
6 · The paper itself

Abstract

For the monitoring of bone regeneration processes, the instrumentation of the fixation is an increasingly common technique to indirectly measure the evolution of bone formation instead of ex vivo measurements or traditional in vivo techniques, such as X-ray or visual review. A versatile instrumented external fixator capable of adapting to multiple bone regeneration processes was designed, as well as a wireless acquisition system for the data collection. The design and implementation of the overall architecture of such a system is described in this work, including the hardware, firmware, and mechanical components. The measurements are conditioned and subsequently sent to a PC via wireless communication to be in vivo displayed and analyzed using a developed real-time monitoring application. Moreover, a model for the in vivo estimation of the bone callus stiffness from collected data was defined. This model was validated in vitro using elastic springs, reporting promising results with respect to previous equipment, with average errors and uncertainties below 6.7% and 14.04%. The devices were also validated in vivo performing a bone lengthening treatment on a sheep metatarsus. The resulting system allowed the in vivo mechanical characterization of the bone callus during experimentation, providing a low-cost, simple, and highly reliable solution.

Indexed as

Bony CallusMetatarsal BonesMonitoring, PhysiologicAnimalsBone RegenerationExternal FixatorsRadiographySheepbone regenerationcalibrationcallus stiffnessexternal fixatorload sensorwireless acquisition system

Identifiers

PMID32824259
PMCPMC7472372
OpenAlexW3049591472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.