Evidence map›Paper›PMID 32824189›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Advanced Glycation End Product Accumulation in Subjects with Open-Angle Glaucoma with and without Exfoliation.

Tomoki Shirakami, Mikihiro Yamanaka, Jo Fujihara, Yotaro Matsuoka, Yuko Gohto, Akira Obana, Masaki Tanito

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Tomoki ShirakamiDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo 693-8501, Japan.ORCID 0000-0003-0019-8857
Mikihiro YamanakaLaboratory of Food and Regulation Biology, School of Agriculture, Tokai University, Kumamoto 862-8652, Japan.
Jo FujiharaDivision of Ophthalmology, Matsue Red Cross Hospital, Matsue 690-8506, Japan.
Yotaro MatsuokaDivision of Ophthalmology, Matsue Red Cross Hospital, Matsue 690-8506, Japan.
Yuko GohtoDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Akira ObanaDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.ORCID 0000-0001-7930-3618
Masaki TanitoDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo 693-8501, Japan.
Matsue Red Cross Hospital · JPSeirei Hamamatsu General Hospital · JPShimane University · JPKyushu Tokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced glycation end products (AGEs), which are the products of a non-enzymatic reaction between reducing sugars and other macromolecules, are critical in aging, as well as metabolic and degenerative diseases. To assess the involvement of AGEs in glaucoma, skin autofluorescence (sAF) level, which is a measurement of AGEs' accumulation, was compared among Japanese patients with glaucoma (316 with primary open-angle glaucoma (PG) and 127 exfoliation syndrome and glaucoma (EG)) and controls (133 nonglaucomatous controls) (mean age 71.6 ± 12.8 years, 254 men and 322 women). The sAF values were estimated from the middle fingertip using a 365 nm light-emitting diode for excitation and detection at 440 nm emission light. The estimated AGE values (arbitrary unit) were 0.56 ± 0.15, 0.56 ± 0.11, and 0.61 ± 0.11 in the control, PG, and EG groups, respectively (

Indexed as

advanced glycation end products (AGEs)AGEs Sensorexfoliation glaucomaoxidative stressprimary open-angle glaucomapseudoexfoliation syndromeskin autofluorescence (sAF)

Identifiers

PMID32824189
PMCPMC7465686
OpenAlexW3049062057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.