Evidence map›Paper›PMID 32824129›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Synthesis and Cytotoxicity Studies of Wood-Based Cationic Cellulose Nanocrystals as Potential Immunomodulators.

Yusha Imtiaz, Beza Tuga, Christopher W Smith, Alexander Rabideau, Long Nguyen, Yali Liu, Sabahudin Hrapovic, Karina Ckless, Rajesh Sunasee

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Synthesis, Applications and Biological Impact of Nanocellulose.Nanomaterials (Basel, Switzerland) · 2022
    Article
  6. Review
  7. Cellulose-Based Nanomaterials Advance Biomedicine: A Review.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yusha ImtiazDepartment of Chemistry, State University of New York at Plattsburgh, Plattsburgh, New York, NY 12901, USA.
Beza TugaDepartment of Chemistry, State University of New York at Plattsburgh, Plattsburgh, New York, NY 12901, USA.
Christopher W SmithDepartment of Chemistry, State University of New York at Plattsburgh, Plattsburgh, New York, NY 12901, USA.ORCID 0000-0002-0828-3370
Alexander RabideauDepartment of Chemistry, State University of New York at Plattsburgh, Plattsburgh, New York, NY 12901, USA.
Long NguyenDepartment of Chemistry, State University of New York at Plattsburgh, Plattsburgh, New York, NY 12901, USA.
Yali LiuAquatic and Crop Resource Development Research Centre, National Research Council Canada, Montreal, QC H4P 2R2, Canada.
Sabahudin HrapovicAquatic and Crop Resource Development Research Centre, National Research Council Canada, Montreal, QC H4P 2R2, Canada.
Karina CklessDepartment of Chemistry, State University of New York at Plattsburgh, Plattsburgh, New York, NY 12901, USA.
Rajesh SunaseeDepartment of Chemistry, State University of New York at Plattsburgh, Plattsburgh, New York, NY 12901, USA.

Funding

National Science Foundation 1703890
6 · The paper itself

Abstract

Polysaccharides have been shown to have immunomodulatory properties. Modulation of the immune system plays a crucial role in physiological processes as well as in the treatment and/or prevention of autoimmune and infectious diseases. Cellulose nanocrystals (CNCs) are derived from cellulose, the most abundant polysaccharide on the earth. CNCs are an emerging class of crystalline nanomaterials with exceptional physico-chemical properties for high-end applications and commercialization prospects. The aim of this study was to design, synthesize, and evaluate the cytotoxicity of a series of biocompatible, wood-based, cationic CNCs as potential immunomodulators. The anionic CNCs were rendered cationic by grafting with cationic polymers having pendant

Indexed as

cellulose nanocrystalscharacterizationcytotoxicityimmunomodulatorpolymerizationsynthesis

Identifiers

PMID32824129
PMCPMC7466698

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.