Evidence map›Paper›PMID 32823996›Full record

ArticleInternational journal of molecular sciences2020

Hypothermically Stored Adipose-Derived Mesenchymal Stromal Cell Alginate Bandages Facilitate Use of Paracrine Molecules for Corneal Wound Healing.

Olla Al-Jaibaji, Stephen Swioklo, Alex Shortt, Francisco C Figueiredo, Che J Connon

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Olla Al-JaibajiBiosciences Institute, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK.ORCID 0000-0002-1185-1973
Stephen SwiokloBiosciences Institute, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK.
Alex ShorttUCL Institute of Ophthalmology, London EC1V 9EL, UK.
Francisco C FigueiredoBiosciences Institute, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK.
Che J ConnonBiosciences Institute, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK.
Centre for Life · GBRoyal Victoria Infirmary · GBUniversity College London · GB

Funding

Department of Health PB-PG-1215-20037Medical Research Council G0900879Medical Research Council MR/S035826/1
6 · The paper itself

Abstract

Adipose-derived mesenchymal stromal cells (Ad-MSCs) may alleviate corneal injury through the secretion of therapeutic factors delivered at the injury site. We aimed to investigate the therapeutic factors secreted from hypothermically stored, alginate-encapsulated Ad-MSCs' bandages in in vitro and in vivo corneal wounds. Ad-MSCs were encapsulated in 1.2%

Indexed as

Paracrine CommunicationPreservation, BiologicalWound HealingAlginatesAnimalsBiomarkersCell SurvivalCorneaGene Expression RegulationHumansMesenchymal Stem CellsMiceModels, BiologicalSolubilityStromal CellsTranscription, GeneticAlginatesBiomarkersadipose-derived stem cellscorneahypothermic storageparacrine factorssodium alginatestem cells bandagewound model

Identifiers

PMID32823996
PMCPMC7461547
OpenAlexW3049764063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.