Trial reportNutrients2020
The Effect of a Multivitamin and Mineral Supplement on Immune Function in Healthy Older Adults: A Double-Blind, Randomized, Controlled Trial.
Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Effects of micronutrient supplementation on immune function in older adults: a meta-analysis.Frontiers in immunology · 2026Pooled it
- Effects of Coenzyme Q10 Supplementation on Physical Function Adaptations to High-Intensity Interval Training in Older Adults.Nutrients · 2025Trial
- Trial
- Gut microbiota and aging: current understanding and future perspectives.Molecular biomedicine · 2026Review
- A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation.Cureus · 2026Review
- Planetary health diet index and risk of mortality and cardiovascular disease: evidence from the health and retirement study.Nutrition journal · 2026Article
- The immune system as a guardian of health: micronutrient support and lifelong protection.Frontiers in nutrition · 2026Review
- The role of multivitamin and mineral supplements in supporting health and well-being: a retrospective cross-sectional study in Taiwan.Journal of health, population, and nutrition · 2025Article
- "Common questions and misconceptions about dietary supplements and the industry - What does science and the law really say?"Journal of the International Society of Sports Nutrition · 2025Review
- Immunocyte-mediated food intakes and colorectal cancer causal relationship insights from a large-scale Mendelian randomization study.Annals of medicine and surgery (2012) · 2025Article
- Multivitamin-mineral supplementation prevents acute upper respiratory tract infections.Asia Pacific journal of clinical nutrition · 2025Article
- Nutrition, Gut Microbiota, and Epigenetics in the Modulation of Immune Response and Metabolic Health.Cardiology and cardiovascular medicine · 2025Article
- Machine learning models for mortality prediction in critically ill patients with acute pancreatitis-associated acute kidney injury.Clinical kidney journal · 2024Article
- Article
- Age-associated changes in innate and adaptive immunity: role of the gut microbiota.Frontiers in immunology · 2024Review
- The Role of Vitamin D in Cardiovascular Diseases.Nutrients · 2023Article
- Changes in Reported Dietary Supplement Use in Cognitively Normal National Alzheimer's Coordinating Center Participants Aged 55 and Older From 2015 to 2019.The Journal of nutrition · 2023Article
- How can we modulate aging through nutrition and physical exercise? An epigenetic approach.Aging · 2023Review
- Emerging cellular senescence-centric understanding of immunological aging and its potential modulation through dietary bioactive components.Biogerontology · 2022Review
- Dietary Supplement Use among Older Cancer Survivors: Socio-Demographic Associations, Supplement Types, Reasons for Use, and Cost.Nutrients · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Older adults are at increased risk for vitamin and mineral deficiencies that contribute to age-related immune system decline. Several lines of evidence suggest that taking a multi-vitamin and mineral supplement (MVM) could improve immune function in individuals 55 and older. To test this hypothesis, we provided healthy older adults with either an MVM supplement formulated to improve immune function (Redoxon
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.