Evidence map›Paper›PMID 32823947›Full record

ArticleInternational journal of molecular sciences2020

Evidence for Enhanced Exosome Production in Aromatase Inhibitor-Resistant Breast Cancer Cells.

Giuseppina Augimeri, Giusi La Camera, Luca Gelsomino, Cinzia Giordano, Salvatore Panza, Diego Sisci, Catia Morelli, Balázs Győrffy, Daniela Bonofiglio, Sebastiano Andò and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

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  12. Obesity and endocrine therapy resistance in breast cancer: Mechanistic insights and perspectives.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Giuseppina AugimeriDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Giusi La CameraDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Luca GelsominoDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Cinzia GiordanoDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Salvatore PanzaDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Diego SisciDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.ORCID 0000-0001-6577-1541
Catia MorelliDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.ORCID 0000-0002-9407-0805
Balázs GyőrffyBioinformatics and 2nd Department of Pediatrics, Semmelweis University, 1094 Budapest, Hungary.
Daniela BonofiglioDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.ORCID 0000-0002-4142-0496
Sebastiano AndòDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Ines BaroneDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.ORCID 0000-0002-9769-1615
Stefania CatalanoDepartment of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
University of Calabria · ITSemmelweis University · HU

Funding

Associazione Italiana per la Ricerca sul Cancro IG #18602Associazione Italiana per la Ricerca sul Cancro IG #21414Associazione Italiana per la Ricerca sul Cancro MFAG #16899Ministero dell'Istruzione, dell'Università e della Ricerca BANDO PRIN 2017 # 2017EKMFTN_001Ministero dell'Istruzione, dell'Università e della Ricerca BANDO PRIN 2017 # 2017WNKSLR_005
6 · The paper itself

Abstract

Aromatase inhibitors (AIs) represent the standard anti-hormonal therapy for post-menopausal estrogen receptor-positive breast cancer, but their efficacy is limited by the emergence of AI resistance (AI

Indexed as

Drug Resistance, NeoplasmAromatase InhibitorsBreast NeoplasmsCluster AnalysisEstrogensExosomesFemaleGene Expression Regulation, NeoplasticHumansMCF-7 CellsProteomicsrab GTP-Binding ProteinsUp-RegulationAromatase InhibitorsEstrogensrab GTP-Binding Proteinsbreast cancerendocrine resistanceexosomesRab GTPases

Identifiers

PMID32823947
PMCPMC7461508
OpenAlexW3049369740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.