Evidence map›Paper›PMID 32823923›Full record

ArticlePathogens (Basel, Switzerland)2020

Coordinated In Vitro Release of Granulysin, Perforin and IFN-γ in TB and HIV/TB Co-Infection Associated with Clinical Outcomes before and after Anti-TB Treatment.

Nada Pitabut, Panadda Dhepakson, Shinsaku Sakurada, Naoto Keicho, Srisin Khusmith

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. CD4Open life sciences · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Nada PitabutFaculty of Medicine, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.ORCID 0000-0002-4888-3178
Panadda DhepaksonMedical Biotechnology Center, Medical Life Sciences Institute, Department of Medical Sciences, Ministry of Public Health, Nonthaburi 11000, Thailand.
Shinsaku SakuradaBureau of International Medical Cooperation, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
Naoto KeichoDepartment of Pathophysiology and Host Defense, The Research Institute of Tuberculosis-Japan Anti-Tuberculosis Association, Tokyo 204-8533, Japan.ORCID 0000-0001-8232-9448
Srisin KhusmithDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Japan Anti Tuberculosis Association · JPKing Mongkut's Institute of Technology Ladkrabang · THMahidol University · THMinistry of Public Health · THNational Center for Global Health and Medicine · JP

Funding

Health and Labor Science Research Grants for Research on Emerging and Re-emerging Infectious Diseases H17-shinko-021 and H20-shinko-014Ministry of Health, Labor and Welfare, Japan; and Global Health and Medicine 17C-1 and 20C-3
6 · The paper itself

Abstract

Granule-associated killing molecules released from cytotoxic T lymphocytes participate as a crucial step in immunity against tuberculosis (TB), but the role of coordinated production remains controversial. Coordinated release of effector molecules in vitro after stimulating peripheral blood mononuclear cells (PBMCs) of active TB or HIV/TB coinfection patients with PPD, purified protein derivative of tuberculin and avirulent

Indexed as

anti-TB treatmentgranulysingranzyme-BH37RaIFN-γin vitroperforinPPD

Identifiers

PMID32823923
PMCPMC7459825
OpenAlexW3049511694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.