Evidence map›Paper›PMID 32823912›Full record

ArticleMaterials (Basel, Switzerland)2020

Expanding Canonical Spider Silk Properties through a DNA Combinatorial Approach.

Zaroug Jaleel, Shun Zhou, Zaira Martín-Moldes, Lauren M Baugh, Jonathan Yeh, Nina Dinjaski, Laura T Brown, Jessica E Garb, David L Kaplan

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. High-yield spidroin mimics for bioinspired fibers via computational design.Frontiers in bioengineering and biotechnology · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Recombinant Spider Silk: Promises and Bottlenecks.Frontiers in bioengineering and biotechnology · 2022
    Review
  8. Review
  9. Multicomponent nature underlies the extraordinary mechanical properties of spider dragline silk.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Zaroug JaleelDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.
Shun ZhouDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.
Zaira Martín-MoldesDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.ORCID 0000-0002-2932-8064
Lauren M BaughDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.
Jonathan YehDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.ORCID 0000-0001-7608-566X
Nina DinjaskiDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.
Laura T BrownDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.
Jessica E GarbDepartment of Biological Science, University of Massachusetts Lowell, 198 Riverside Street, Olsen Hall 234, Lowell, MA 01854, USA.
David L KaplanDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.ORCID 0000-0002-9245-7774
Tufts University · USBoston University · USUniversity of Massachusetts Lowell · US

Funding

TRAINING GRANTS IN ENVIROMENTAL TOXICOLOGYT32ES007020 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ESSIGMANN, JOHN M · 1985 to 2024
$13.1M
Models to Predict Protein Biomaterial PerformanceU01EB014976 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI BUEHLER, MARKUS J., KAPLAN, DAVID L. · 2012 to 2020
$5.2M
Air Force Office of Scientific Research FA9550-14-1-0015NIBIB NIH HHS U01 EB014976NIEHS NIH HHS T32 ES007020NIH HHS U01EB014976
6 · The paper itself

Abstract

The properties of native spider silk vary within and across species due to the presence of different genes containing conserved repetitive core domains encoding a variety of silk proteins. Previous studies seeking to understand the function and material properties of these domains focused primarily on the analysis of dragline silk proteins, MaSp1 and MaSp2. Our work seeks to broaden the mechanical properties of silk-based biomaterials by establishing two libraries containing genes from the repetitive core region of the native

Indexed as

biomaterialsbroadening silk propertiesrecombinant spider silk

Identifiers

PMID32823912
PMCPMC7475873
OpenAlexW3049112982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.