Evidence map›Paper›PMID 32823844›Full record

ArticleJournal of clinical medicine2020

The Role of Iron and Erythropoietin in the Association of Fibroblast Growth Factor 23 with Anemia in Chronic Kidney Disease in Humans.

Bernhard Bielesz, Thomas Reiter, Fabian Peter Hammerle, Wolfgang Winnicki, Marija Bojic, Andreas Gleiss, Heidi Kieweg, Franz Ratzinger, Gere Sunder-Plassmann, Rodrig Marculescu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bernhard BieleszDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, 1090 Vienna, Austria.
Thomas ReiterDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, 1090 Vienna, Austria.
Fabian Peter HammerleDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-7755-4445
Wolfgang WinnickiDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-0511-6120
Marija BojicDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-9732-4439
Andreas GleissCenter for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, 1090 Vienna, Austria.
Heidi KiewegDepartment of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Franz RatzingerDepartment of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Gere Sunder-PlassmannDivision of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-9253-9921
Rodrig MarculescuDepartment of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-1772-6695
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anemia in chronic kidney disease (CKD) is an almost universal complication of this condition. Fibroblast growth factor 23 (FGF23), a key-player in mineral metabolism, is reportedly associated with anemia and hemoglobin levels in non-dialysis CKD patients. Here, we sought to further characterize this association while taking into account the biologically active, intact fraction of FGF23, iron metabolism, and erythropoietin (EPO). Hemoglobin, EPO, iron, and mineral metabolism parameters, including both intact and c-terminal-FGF23 (iFGF23 and cFGF23, respectively) were measured cross-sectionally in 225 non-dialysis CKD patients (stage 1-5, median eGFR: 30 mL/min./1.73m

Indexed as

anemiachronicmineral metabolismrenal insufficiency

Identifiers

PMID32823844
PMCPMC7463779
OpenAlexW3048819657

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.