Evidence map›Paper›PMID 32823823›Full record

ArticlePharmaceutics2020

Hybrid Pectin-Liposome Formulation against Multi-Resistant Bacterial Strains.

Lígia Nunes de Morais Ribeiro, Eneida de Paula, Daise Aparecida Rossi, Guilherme Paz Monteiro, Edson Campos Valadares Júnior, Rogério Reis Silva, Rodrigo Rodrigues Franco, Foued Salmen Espíndola, Luiz Ricardo Goulart, Belchiolina Beatriz Fonseca

Abstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lígia Nunes de Morais RibeiroSchool of Veterinary Medicine, Federal University of Uberlândia, Uberlândia 38402-018, Brazil.ORCID 0000-0001-6097-5449
Eneida de PaulaDepartment of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas 13083-862, Brazil.ORCID 0000-0003-4504-5723
Daise Aparecida RossiSchool of Veterinary Medicine, Federal University of Uberlândia, Uberlândia 38402-018, Brazil.
Guilherme Paz MonteiroSchool of Veterinary Medicine, Federal University of Uberlândia, Uberlândia 38402-018, Brazil.
Edson Campos Valadares JúniorSchool of Veterinary Medicine, Federal University of Uberlândia, Uberlândia 38402-018, Brazil.
Rogério Reis SilvaSchool of Veterinary Medicine, Federal University of Uberlândia, Uberlândia 38402-018, Brazil.
Rodrigo Rodrigues FrancoInstitute of Biotechnology, Federal University of Uberlândia, Uberlândia 38405-319, Brazil.
Foued Salmen EspíndolaInstitute of Biotechnology, Federal University of Uberlândia, Uberlândia 38405-319, Brazil.ORCID 0000-0002-6937-1411
Luiz Ricardo GoulartInstitute of Biotechnology, Federal University of Uberlândia, Uberlândia 38405-319, Brazil.ORCID 0000-0002-1803-4861
Belchiolina Beatriz FonsecaSchool of Veterinary Medicine, Federal University of Uberlândia, Uberlândia 38402-018, Brazil.ORCID 0000-0001-8485-078X

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 465669/2014-0Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.336865/2019-00
6 · The paper itself

Abstract

This work describes the development of a gastroresistant antimicrobial formulation composed of two carriers, pectin and liposomes, intended to improve the efficiency of norfloxacin (NOR) against multi-resistant bacterial strains. The formulations showed physicochemical stability for 180 days (4 °C) in terms of size, polydispersity, and zeta potential of the vesicles, prolonging the in vitro release of NOR for 11 h. The hybrid nanocarriers improved the in vitro antimicrobial activity against different multidrug-resistant bacterial strains, such as

Indexed as

biopolymersdrug deliveryfluoroquinoloneshybrid formulationsliposomesmultidrug resistance

Identifiers

PMID32823823
PMCPMC7465986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.