Evidence map›Paper›PMID 32823780›Full record

ArticleCells2020

A Novel Approach for Detecting Unique Variations among Infectious Bacterial Species in Endocarditic Cardiac Valve Vegetation.

Nadji Hannachi, Hubert Lepidi, Anthony Fontanini, Tatsuki Takakura, Jacques Bou-Khalil, Frédérique Gouriet, Gilbert Habib, Didier Raoult, Laurence Camoin-Jau, Jean-Pierre Baudoin

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. The impact of thrombocytopenia on mortality in infective endocarditis - aInternational journal of cardiology. Heart & vasculature · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. UnderstandingCells · 2023
    Article
  7. The Role of Platelets in Infective Endocarditis.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. A Massive Number of ExtracellularFrontiers in immunology · 2022
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Nadji HannachiAix Marseille Univ, IRD, APHM, MEPHI, IHU Méditerranée Infection, 13005 Marseille, France.
Hubert LepidiLaboratoire D'anatomie et de Cytologie Pathologique, Hôpital de la Timone, AP-HM, boulevard Jean-Moulin, 13005 Marseille, France.
Anthony FontaniniAix Marseille Univ, IRD, APHM, MEPHI, IHU Méditerranée Infection, 13005 Marseille, France.
Tatsuki TakakuraHitachi High-Tech Corporation, Analytical & Medical Solution Business Group 882 Ichige, Hitachinaka-shi, Ibaraki-ken 312-8504, Japan.
Jacques Bou-KhalilAix Marseille Univ, IRD, APHM, MEPHI, IHU Méditerranée Infection, 13005 Marseille, France.
Frédérique GourietAix Marseille Univ, IRD, APHM, MEPHI, IHU Méditerranée Infection, 13005 Marseille, France.
Gilbert HabibDépartement de Cardiologie, Hôpital de la Timone, AP-HM, Boulevard Jean-Moulin, 13005 Marseille, France.
Didier RaoultAix Marseille Univ, IRD, APHM, MEPHI, IHU Méditerranée Infection, 13005 Marseille, France.
Laurence Camoin-JauAix Marseille Univ, IRD, APHM, MEPHI, IHU Méditerranée Infection, 13005 Marseille, France.
Jean-Pierre BaudoinAix Marseille Univ, IRD, APHM, MEPHI, IHU Méditerranée Infection, 13005 Marseille, France.ORCID 0000-0001-7361-5653
Méditerranée Infection Foundation · FRHôpital de la Timone · FRHitachi High-Tech (Japan)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious endocarditis (IE) remains one of the deadliest heart diseases with a high death rate, generally following thrombo-embolic events. Today, therapy is based on surgery and antibiotic therapy. When thromboembolic complications in IE patients persist, this is often due to our lack of knowledge regarding the pathophysiological development and organization of cells in the vegetation, most notably the primordial role of platelets and further triggered hemostasis, which is related to the diversity of infectious microorganisms involved. Our objective was to study the organization of IE vegetations due to different bacteria species in order to understand the related pathophysiological mechanism of vegetation development. We present an approach for ultrastructural analysis of whole-infected heart valve tissue based on scanning electron microscopy and energy-dispersive X-ray spectroscopy. Our approach allowed us to detect differences in cell organization between the analyzed vegetations and revealed a distinct chemical feature in

Indexed as

AgedAged, 80 and overBlood PlateletsEndocarditis, BacterialFemaleFibrinGram-Positive BacteriaGram-Positive Bacterial InfectionsHeart ValvesHumansInflammationMaleMicroscopy, Electron, ScanningMiddle AgedSpectrometry, X-Ray EmissionFibrinbacteriaEDXinfectious endocarditisSEMvegetation

Identifiers

PMID32823780
PMCPMC7464176
OpenAlexW3048658321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.