Evidence map›Paper›PMID 32823723›Full record

ReviewInternational journal of molecular sciences2020

Becoming Stressed: Does the Age Matter? Reviewing the Neurobiological and Socio-Affective Effects of Stress throughout the Lifespan.

Aroa Mañas-Ojeda, Francisco Ros-Bernal, Francisco E Olucha-Bordonau, Esther Castillo-Gómez

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Relaxin-3 Receptor, RXFP3, Is a Modulator of Aging-Related Disease.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aroa Mañas-OjedaDepartment of Medicine, School of Medical Sciences, Universitat Jaume I, 12071 Castellón de la Plana, Spain.
Francisco Ros-BernalDepartment of Medicine, School of Medical Sciences, Universitat Jaume I, 12071 Castellón de la Plana, Spain.ORCID 0000-0001-9072-929X
Francisco E Olucha-BordonauDepartment of Medicine, School of Medical Sciences, Universitat Jaume I, 12071 Castellón de la Plana, Spain.ORCID 0000-0003-0342-993X
Esther Castillo-GómezDepartment of Medicine, School of Medical Sciences, Universitat Jaume I, 12071 Castellón de la Plana, Spain.ORCID 0000-0002-7566-0340

Funding

Fundación Alicia Koplowitz 19I436Generalitat Valenciana GV/2019/088Ministerio de Ciencia e Innovación RTI2018-095698-B-I00Universitat Jaume I UJI-A2017-17Universitat Jaume I UJI-B2019-54
6 · The paper itself

Abstract

Social and affective relations occur at every stage of our lives. Impairments in the quality of this "social world" can be exceptionally detrimental and lead to psychopathology or pathological behavior, including schizophrenia, autism spectrum disorder, affective disorders, social phobia or violence, among other things. Exposure to highly stressful or traumatic events, depending on the stage of life in which stress exposure occurs, could severely affect limbic structures, including the amygdala, and lead to alterations in social and affective behaviors. This review summarizes recent findings from stress research and provides an overview of its age-dependent effects on the structure and function of the amygdala, which includes molecular and cellular changes, and how they can trigger deviant social and affective behaviors. It is important to highlight that discoveries in this field may represent a breakthrough both for medical science and for society, as they may help in the development of new therapeutic approaches and prevention strategies in neuropsychiatric disorders and pathological behaviors.

Indexed as

Social BehaviorAnimalsHumansLongevityModels, BiologicalStress, Psychologicaladultamygdalaanxietydepressionearly lifeendocannabinoidneuronal plasticityold agesociabilitystress

Identifiers

PMID32823723
PMCPMC7460954

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.